秦娜，博士，校聘教授，国家重大人才工程B类（青年项目）入选者。St. Jude Children’s Research Hospital访问学者，中国抗癌协会肺癌防筛专委会委员。主要致力于复杂疾病的基因组流行病学研究。主持国家自然科学基金、江苏省自然科学基金、中国博士后基金等科研项目6项；以第一或通讯（含并列）作者在Lancet Oncology、Journal of Clinical Oncology、Cancer Cell等期刊发表论文20余篇。
研究方向：基因组流行病学
联系方式：
地址：南京市江宁区龙眠大道101号至诚楼572室
邮箱：naqin@njmu.edu.cn
主要在研项目
1. 国家重大人才工程B类（青年项目），DNA损伤修复基因非编码罕见致病变异影响肺癌风险的关联和机制研究，2024.01-2026.12，主持。
2. 国家自然科学基金青年项目，染色体2q33.1区域遗传变异调控CASP8基因表达影响肺癌易感性的分子流行病学研究，2022.01-2024.12，结题。
3. 江苏省自然科学基金青年项目，染色体2q33.1区域胚系遗传变异影响肺癌易感性的分子流行病学研究，2021.07-2023.06，结题。
代表性论文：
1. Qin N#, Wang C#, Chen C#, Yang L#, Liu S, Xiang J, Xie Y, Liang S, Zhou J, Xu X, Zhao X, Zhu M, Jin G, Ma H, Dai J, Hu Z*, Shen H*. Association of the interaction between mosaic chromosomal alterations and polygenic risk score with the risk of lung cancer: an array-based case-control association and prospective cohort study. Lancet Oncol. 2022 Nov;23(11):1465-1474.
2. Chen C#, Qin N#, Wang M#, Dong Q, Tithi SS, Hui Y, Chen W, Wu G, Kennetz D, Edmonson MN, Rusch MC, Thrasher A, Easton J, Mulder HL, Song N, Plonski NM, Shelton K, Im C, Ehrhardt MJ, Nichols KE, Leisenring WM, Stratton KL, Howell R, Yasui Y, Bhatia S, Armstrong GT, Ness KK, Hudson MM, Zhang J, Wang H, Srivastava DK, Robison LL, Wang Z*. Cancer germline predisposing variants and late mortality from subsequent malignant neoplasms among long-term childhood cancer survivors: a report from the St Jude Lifetime Cohort and the Childhood Cancer Survivor Study. Lancet Oncol. 2023 Oct;24(10):1147-1156.
3. Wang C#, Dai J#, Qin N#, Fan J#, Ma H#, Chen C#, An M, Zhang J, Yan C, Gu Y, Xie Y, He Y, Jiang Y, Zhu M, Song C, Jiang T, Liu J, Zhou J, Wang N, Hua T, Liang S, Wang L, Xu J, Yin R, Chen L, Xu L, Jin G, Lin D, Hu Z*, Shen H*. Analyses of rare predisposing variants of lung cancer in 6,004 whole genomes in Chinese. Cancer Cell. 2022 Oct 10;40(10):1223-1239.e6.
4. Qin N#, Li Z#, Song N#, Wilson CL, Easton J, Mulder H, Plyler E, Neale G, Walker E, Zhou X, Pan H, Hudson MM, Yasui Y, Robison LL, Zhang J, Ness KK, Wang Z*. Epigenetic Age Acceleration and Chronic Health Conditions among Adult Survivors of Childhood Cancer. J Natl Cancer Inst. 2021 May 4;113(5):597-605.
5. Qin N#, Wang Z#*, Liu Q#, Song N, Wilson CL, Ehrhardt MJ, Shelton K, Easton J, Mulder HL, Kennetz D, Edmonson MN, Rusch M, Downing JR, Hudson MM, Nichols KE, Zhang J, Robison LL, Yasui Y. Pathogenic germline mutations in DNA-Repair genes in combination with cancer treatment exposures and risk of subsequent neoplasms among long-term survivors of childhood cancer. J Clin Oncol. 2020 Aug 20;38(24):2728-2740.
6. Qin N#, Li Y#, Wang C, Zhu M, Dai J, Hong T, Albanes D, Lam S, Tardon A, Chen C, Goodman G, Bojesen S, Landi MT, Johansson M, Risch A, Wichmann HE, Bickeboller H, Rennert G, Arnold S, Brennan P, Field JK, Shete S, Marchand LL, Melander O, Brunnstrom H, Liu G, Hung RJ, Andrew A, Kiemeney LA, Zienolddiny S, Grankvist K, Johansson M, Caporaso N, Woll P, Lazarus P, Schabath MB, Aldrich MC, Stevens VL, Jin G, Christiani DC, Hu Z, Amos CI, Ma H*, Shen H*. Comprehensive functional annotation of susceptibility variants identifies genetic heterogeneity between lung adenocarcinoma and squamous cell carcinoma. Frontiers of Medicine. 2021 Apr;15(2):275-291.
7. Qin N#, Ma Z#, Wang C#, Zhang E, Li Y, Huang M, Chen C, Zhang C, Fan J, Gu Y, Xu X, Yang L, Wei X, Yin R, Jiang Y, Dai J, Jin G, Xu L, Hu Z, Shen H*, Ma H*. Comprehensive characterization of functional eRNAs in lung adenocarcinoma reveals novel regulators and a prognosis-related molecular subtype. Theranostics. 2020 Sep 14;10(24):11264-11277.
8. Qin N#, Li N#, Wang C#, Pu Z#, Ma Z, Jin G, Zhu M, Dai M, Hu Z, Ma H, Shen H*. Association of mosaic loss of chromosome Y with lung cancer risk and prognosis in a Chinese population. J Thorac Oncol. 2019 Jan;14(1):37-44.
9. Dai J#, Lv J#, Zhu M#, Wang Y#, Qin N#, Ma H#, He YQ#, Zhang R#, Tan W, Fan J, Wang T, Zheng H, Sun Q, Wang L, Huang M, Ge Z, Yu C, Guo Y, Wang TM, Wang J, Xu L, Wu W, Chen L, Bian Z, Walters R, Millwood IY, Li XZ, Wang X, Hung RJ, Christiani DC, Chen H, Wang M, Wang C, Jiang Y, Chen K, Chen Z, Jin G, Wu T, Lin D, Hu Z, Amos CI, Wu C, Wei Q, Jia WH, Li L, Shen H*. Identification of risk loci and a polygenic risk score for lung cancer: a large-scale prospective cohort study in Chinese populations. Lancet Respir Med. 2019 Oct;7(10):881-891.