尹先勇，医学博士，流行病学教授，博士生导师。2005年在安徽医科大学获医学学士学位并留校任教，2009年获安徽医科大学皮肤病与性病学硕士学位，2014年获安徽医科大学皮肤病与性病学博士学位。2014年至2015年任安徽医科大学皮肤病研究所副教授，2015年至2017年任美国北卡大学教堂山分校遗传学系研究助理教授，2017年至2023年在美国密歇根大学安娜堡分校生物统计学系从事博士后研究，2023年起任南京医科大学流行病学系教授。主要从事炎症与代谢性疾病的遗传流行病学研究，共发表SCI论文80余篇，其中以第一/通讯作者（含并列）在Ann Rheum Dis、Am J Hum Genet、Nat Commun等杂志发表论文26篇，他引6000余次，H指数33；主译《遗传统计学》（人民卫生出版社）。主持完成国家自然科学基金青年基金、国家自然科学基金面上项目、安徽省杰出青年基金、美国糖尿病学会（ADA）博士后研究基金等项目研究。以主要参与者身份获2016年中华医学科技奖一等奖和2021年中华医学科技奖三等奖；入围美国人类遗传学会（ASHG）2022年Charles J Epstein奖，美国密歇根大学2018年精准医学青年学者奖，理肤泉（LA ROCHE-POSAY）亚太基金会2016年优秀基础研究论文奖、美国实验皮肤科学会（SID）2015年Albert M. Kligman奖等。应邀担任Genetics in Medicine杂志编委（Editorial board member）和Phenomics杂志青年编委，曾任 British Journal of Dermatology杂志副主编（Associate editor）。
研究方向：炎症与代谢性疾病的遗传流行病学
联系方式：
地址：南京市江宁区龙眠大道101号南京医科大学至诚楼G441
代表性论文 (*：并列第一作者；#：并列通讯作者)
1. Yin X, Bose D, Kwon A, Hanks SC, Jackson AU, Stringham HM, Welch R, Oravilahti A, Fernandes Silva L, FinnGen, Locke AE, Fuchsberger C, Service SK, Erdos MR, Bonnycastle LL, Kuusisto J, Stitziel NO, Hall IM, Morrison J, Ripatti S, Palotie A, Freimer NB, Collins FS, Mohlke KL, Scott LJ, Fauman EB, Burant C, Boehnke M#, Laakso M#, Wen X#. Integrating transcriptomics, metabolomics, and GWAS helps reveal molecular mechanisms for metabolite levels and disease risk.American Journal of Human Genetics.2022 Oct;109(10):1727-1741. PMID: 36055244.
2. Yin X*, Kim K*, Suetsugu H*, Bang S, Wen L, Koido M, Ha E, Liu L, Sakamoto Y, Jo S, Leng R, Otomo N, Laurynenka V, Kwon Y, Sheng Y, Sugano N, Hwang Y, Li W, Mukai M, Yoon K, Cai M, Ishigaki K, Chung W, Huang H, Takahashi D, Lee S, Wang M, Karino K, Shim S, Zheng X, Miyamura T, Kang Y, Ye D, Nakamura J, Suh C, Tang Y, Motomura G, Park Y, Ding H, Kuroda T, Choe J, Li C, Niiro H, Park Y, Shen C, Miyamoto T, Ahn G, Fei W, Takeuchi T, Shin J, Li K, Kawaguchi Y, Lee Y, Wang Y, Amano K, Yang W, Tada Y, Yamaji K, Shimizu M, Atsumi T, Suzuki A, Sumida T, Okada Y, Matsuda K, Matsuo K, Kochi Y, Japanese Research Committee on Idiopathic Osteonecrosis of the Femoral Head, Kottyan L, Weirauch M, Parameswaran S, Eswar S, Salim H, Chen X, Yamamoto K, Harley J, Ohmura K, Kim T, Yang S, Yamamoto T, Kim B, Shen N, Ikegawa S, Lee H, Zhang X, Terao C#, Cui Y#, Bae S#. Biological insights into systemic lupus erythematosus through an immune cell-specific transcriptome-wide association study.Annals of the Rheumatic Diseases. 2022; 81(9):1273-1280. PMID: 35609976.
3. Yin X, Chan LS, Bose D, Jackson AU, VandeHaar P, Locke AE, Fuchsberger C, Stringham HM, Welch R, Yu KT, Silva LF, Service SK, Zhang DW, Hector EC, Young E, Ganel L, Das I, Abel H, Erdos MR, Bonnycastle LL, Kuusisto J, Stitziel NO, Hall I, Wagner GR, FinnGen, Kang J, Morrison J, Burant CF, Collins FS, Ripatti S, Palotie A, Freimer NB, Mohlke KL, Scott LJ, Wen XQ, Fauman EB#, Laakso M#, Boehnke M#. Genome-wide association studies of metabolites in Finnish men identify disease-relevant loci.Nature Communications. 2022; 13:1644. PMID: 35347128.
4. Yin X*, Kim KW*, Suetsugu H*, Bang SY, Wen LL, Koido M, Ha EJ, Liu L, Sakamoto Y, Jo S, Leng RX, Otomo N, Laurynenka V, Kwon YC, Sheng YJ, Sugano N, Hwang MY, Li WR, Mukai M, Yoon K, Cai ML, Ishigaki K, Chung WT, Huang H, Takahashi D, Lee SS, Wang MW, Karino K, Shim SC, Zheng XD, Miyamura T, Kang YM, Ye DQ, Nakamura J, Suh CH, Tang YJ, Motomura G, Park YB, Ding HH, Kuroda T, Choe JY, Li CX, Niiro H, Park Y, Shen CB, Miyamoto T, Ahn GY, Fei WM, Takeuchi T, Shin JM, Li KK, Kawaguchi Y, Lee YK, Wang YF, Amano K, Yang WL, Tada Y, Yamaji K, Shimizu M, Atsumi T, Suzuki A, Sumida T, Okada Y, Matsuda K, Matsuo K, Kochi Y, Japanese Research Committee on Idiopathic Osteone, Kottyan LC, Weirauch MT, Parameswaran S, Eswar S, Salim H, Chen XT, Yamamoto K, Harley JB, Ohmura K, Kim TH, Yang S, Yamamoto T, Kim BJ, Shen N, Ikegawa S, Lee HS, Zhang XJ, Terao C#, Cui Y#, Bae SC#. Meta-analysis of 208370 East Asians identifies 113 susceptibility loci for systemic lupus erythematosus.Annals of the Rheumatic Diseases. 2021;80(5):632-640. PMID: 33272962.
5. Wen L*, Zhu C*, Zhu Z*, Yang C*, Zheng X*, Liu L*, Zuo X, Sheng Y, Tang H, Liang B, Zhou Y, Li P, Zhu J, Ding Y, Chen G, Gao J, Tang L, Cheng Y, Sun J, Elango T, Kafle A, Yu R, Xue K, Zhang Y, Li F, Li Z, Guo J, Zhang X, Zhou C, Tang Y, Shen N, Wang M, Yu X, Liu S, Fan X, Gao M, Xiao F, Wang P, Wang Z, Zhang A, Zhou F, Sun L, Yang S, Xu J, Yin X#, Cui Y#, Zhang X#.Exome-wide association study identifies four novel loci for systemic lupus erythematosus in Han Chinese population. Annals of the Rheumatic Diseases.2018;77(3):417. PMID: 29233832.
6. Lin Y, Liu L, Yang S, Li Y, Lin D, Zhang X, Yin X#. Genotype imputation for Han Chinese population using Haplotype Reference Consortium as reference.Human Genetics. 2018;137(6-7):431-436. PMID: 29855708.
7. Yin X*, Low HQ*, Wang L, Li Y, Ellinghaus E, Han J, Estivill X, Sun L, Zuo X, Shen C, Zhu C, Zhang A, Sanchez F, Padyukov L, Catanese JJ, Krueger GG, Duffin KC, Mucha S, Weichenthal M, Weidinger S, Lieb W, Foo JN, Li Y, Sim K, Liany H, Irwan I, Teo Y, Theng CT, Gupta R, Bowcock A, De Jager PL, Qureshi AA, de Bakker PI, Seielstad M, Liao W, Ståhle M, Franke A#, Zhang X#, Liu J#. Genome-wide meta-analysis identifies multiple novel associations and ethnic heterogeneity of psoriasis susceptibility. Nature Communications. 2015;6:6916. PMID: 25903422.
8. Zuo X*, Sun L*, Yin X*, Gao J*, Sheng Y*, Xu J, Zhang J, He C, Qiu Y, Wen G, Tian H, Zheng X, Liu S, Wang W, Li W, Cheng Y, Liu L, Chang Y, Wang Z, Li Z, Li L, Wu J, Fang L, Shen C, Zhou F, Liang B, Chen G, Li H, Cui Y, Xu A, Yang X, Hao F, Xu L, Fan X, Li Y, Wu R, Wang X, Liu X, Zheng M, Song S, Ji B, Fang H, Yu J, Sun Y, Hui Y, Zhang F, Yang R, Yang S, Zhang X#. Whole exome analysis identifies 15 new psoriasis susceptibility loci for psoriasis.Nature Communications.2015;6:6793. PMID: 25854761.
9. Yin XY*#, Zhang R*, Cheng H, Pan Q, Shen CB, Fan X, Wang ZX, Sun LD, Yang S, Zhang XJ#. Gene-gene interactions between HLA-C, ERAP1, TNFAIP3 and TRAF3IP2 and the risk of psoriasis in the Chinese Han population.British Journal of Dermatology.2013;169(4):941-3. PMID: 23701417.
10. Xu S*, Yin X*, Li S, Jin W, Lou H, Yang L, Gong X, Wang H, Shen Y, Pan X, He Y, Yang Y, Wang Y, Fu W, An Y, Wang J, Tan J, Qian J, Chen X, Zhang X, Sun Y, Zhang X, Wu B, Jin L#. Genomic dissection of population substructure of Han Chinese and its implication in association studies. American Journal of Human Genetics. 2009;85(6):762-74. PMID: 19944404.