杜牧龙，博士，副教授，硕士生导师，南京医科大学公共卫生学院生物统计学系。
研究方向：复杂疾病多组学分析的理论与应用研究
联系方式：
地址：南京市江宁区龙眠大道101号南京医科大学至诚楼G420
电话：025-86868244
邮箱：drdumulong@njmu.edu.cn
承担课题：
国家自然科学基金面上基金项目：环状RNA与红肉代谢途径的基因-环境交互作用参与结直肠癌易感的机制研究（82173601）主持，在研
国家自然科学基金青年基金项目：外泌体环状RNA作为结直肠癌潜在早期生物标志物及其机制研究（81703307）主持，结题
多组学研究：
1. Du M, Garcia JGN, Christie JD, Xin J, Cai G, Meyer NJ, Zhu Z, Yuan Q, Zhang Z, Su L, Shen S, Dong X, Li H, Hutchinson JN, Tejera P, Lin X, Wang M*, Chen F*, Christiani DC*. Integrative omics provide biological and clinical insights into acute respiratory distress syndrome. Intensive Care Med. 2021 May 25;1-11.
2. Du M, Cai G, Chen F, Christiani DC, Zhang Z*, Wang M*. Multiomics Evaluation of Gastrointestinal and Other Clinical Characteristics of COVID-19. Gastroenterology. 2020 Jun;158(8):2298-2301.e7.
风险预测：
3. Ben S#, Xin J#, Chen S#, Jiang Y, Yuan Q, Su L, Christiani DC, Zhang Z*, Du M*, Wang M*. Global internet search trends related to gastrointestinal symptoms predict regional COVID-19 outbreaks. J Infect. 2022 Jan;84(1):56-63.
4. Xin J#, Wu Y#, Ben S, Li S, Chu H, Wang M, Wang M, Song M, Du M*, Zhang Z*. CoSMeD: a user-friendly web server to estimate 5-year survival probability of left-sided and right-sided colorectal cancer patients using molecular data. Bioinformatics. 2021 Jul 14;btab523.
遗传标志物：
5. Meng Y#, Du M#, Gu D#, Li C#, Li S, Zhang Q, Ben S, Zhu Q, Xin J, Zhang Z, Hu Z, Shen H, Jiang K*, Wang M*. Genome-wide association analyses identify CATSPERE as a mediator of colorectal cancer susceptibility and progression. Cancer Res. 2022 Jan 24;canres.2948.2021.
6. Xin J#, Du M#, Jiang X#, Wu Y, Ben S, Zheng R, Chu H, Li S, Zhang Z*, Wang M*. Systematic evaluation of the effects of genetic variants on PIWI-interacting RNA expression across 33 cancer types. Nucleic Acids Res. 2021 Jan 11;49(1):90-97.
7. Du M#, Zheng R#, Ma G#, Chu H#, Lu J, Li S, Xin J, Tong N, Zhang G, Wang W, Qiang F, Gong W, Zhao Q, Tao G, Chen J, Jia Z, Jiang J, Jin G, Hu Z, Shen H, Wang M*, Zhang Z*. Remote modulation of lncRNA GCLET by risk variant at 16p13 underlying genetic susceptibility to gastric cancer. Sci Adv. 2020 May 20;6(21):eaay5525.
效应标志物：
8. Zheng R#, Zhang K#, Tan S#, Gao F, Zhang Y, Xu W, Wang H, Gu D, Zhu L, Li S, Chu H, Zhang Z, Liu L*, Du M*, Wang M*. Exosomal circLPAR1 functions in colorectal cancer diagnosis and tumorigenesis through suppressing BRD4 via METTL3-eIF3h interaction. Mol Cancer. 2022 Feb 14;21(1):49.
9. Wu Y#, Xin J#, Loehrer EA, Jiang X, Yuan Q, Christiani DC, Shi H, Liu L, Li S, Wang M, Chu H*, Du M*, Zhang Z*. High-density lipoprotein, low-density lipoprotein and triglyceride levels and upper gastrointestinal cancers risk: a trans-ancestry Mendelian randomization study. Eur J Clin Nutr. 2022 Jan 21.
10. Zheng R#, Du M#, Tian M#, Zhu Z, Wei C, Chu H, Gan C, Liang J, Xue R, Gao F, Mao Z, Wang M*, Zhang Z*. Fine Particulate Matter Induces Childhood Asthma Attacks via Extracellular Vesicle-Packaged Let-7i-5p-Mediated Modulation of the MAPK Signaling Pathway. Adv Sci (Weinh). 2022 Jan;9(3):e2102460.