靳光付,南京医科大学教授,博士生导师,国家杰出青年科学基金获得者,现任研究生院院长、肿瘤个体化医学省部共建协同创新中心副主任、江苏省恶性肿瘤生物标志物与防治重点实验室副主任。主要从事肿瘤分子与遗传流行病学研究,研究成果发表在Lancet Oncol、Nat Genet、Gastroenterology、Gut、Am J Hum Genet、Cancer Res等国际高水平期刊,累计SCI他引6000余次。以主要完成人获国家自然科学二等奖、教育部自然科学一等奖、江苏省科学技术一等奖等科技奖励,曾获中国肿瘤青年科学家奖。现兼任中国抗癌协会青年理事会常务理事、中国抗癌协会肿瘤病因学和胃肠病学专业委员会常务委员、江苏省医学会临床流行病学分会候任主任委员等。
研究方向:肿瘤分子与遗传流行病学
联系方式:
地址:南京市江宁区龙眠大道101号南京医科大学至诚楼
电话:025-86868397
主要在研项目:
1、国家自然科学基金面上项目(No. 81872702),胚系遗传变异与体细胞突变在胃癌发生中的关联及机制研究,2019.01-2022.12,主持
2、国家杰出青年科学基金项目(No. 82125033),分子与遗传流行病学,2022.01-2026.12,主持
代表性论文:
1. Zhu M, Wang T, Huang Y, Zhao X, Ding Y, Zhu M, Ji M, Wang C, Dai J, Yin R, Xu L, Ma H, Wei Q, Jin G, Hu Z, Shen H. Genetic Risk for Overall Cancer and the Benefit of Adherence to a Healthy Lifestyle.Cancer Res. 2021 Sep;81(17):4618-4627.
2. Jin G, Lv J, Yang M, Wang M, Zhu M, Wang T, Yan C, Yu C, Ding Y, Li G, Ren C, Ni J, Zhang R, Guo Y, Bian Z, Zheng Y, Zhang N, Jiang Y, Chen J, Wang Y, Xu D, Zheng H, Yang L, Chen Y, Walters R, Millwood IY, Dai J, Ma H, Chen K, Chen Z, Hu Z, Wei Q, Shen H, Li L. Genetic risk, incident gastric cancer, and healthy lifestyle: a meta-analysis of genome-wide association studies and prospective cohort study. Lancet Oncol. 2020 Oct; 21(10):1378-1386.
3. Yan C, Zhu M, Ding Y, Yang M, Wang M, Li G, Ren C, Huang T, Yang W, He B, Wang M, Yu F, Wang J, Zhang R, Wang T, Ni J, Chen J, Jiang Y, Dai J, Zhang E, Ma H, Wang Y, Xu D, Wang S, Chen Y, Xu Z, Zhou J, Ji G, Wang Z, Zhang Z, Hu Z, Wei Q, Shen H, Jin G. Meta-analysis of genome-wide association studies and functional assays decipher susceptibility genes for gastric cancer in Chinese populations. Gut. 2020 Apr;69(4):641-651.
4. Ni J, Wang J, Fu Y, Yan C, Zhu M, Jiang Y, Chen J, Ding Y, Fan X, Li G, Jin G. Functional Genetic Variants in Centrosome-Related Genes CEP72 and YWHAG Confer Susceptibility to Gastric Cancer. Arch Toxicol. 2020 Aug;94(8):2861-2872.
5. Yu F, Tian T, Deng B, Wang T, Qi Q, Zhu M, Yan C, Ding H, Wang J, Dai J, Ma H, Ding Y, Jin G. Multi-marker analysis of genomic annotation on gastric cancer GWAS data from Chinese populations. Gastric Cancer. 2019 Jan;22(1):60-68.
6. Yan C, Zhu M, Huang T, Yu F, Jin G. Genome-wide association studies identified loci contribute to phenotypic variance of gastric cancer. Gut. 2018 Jul;67(7):1366-1368.
7. Yan C, Ji Y, Huang T, Yu F, Gao Y, Gu Y, Qi Q, Du J, Dai J, Ma H, Jin G. An esophageal adenocarcinoma susceptibility locus at 9q22 also confers risk to esophageal squamous cell carcinoma by regulating the function of BARX1. Cancer Lett. 2018 May 1;421:103-111.
8. Zhu M, Yan C, Ren C, Huang X, Zhu X, Gu H, Wang M, Wang S, Gao Y, Ji Y, Miao X, Yang M, Chen J, Du J, Huang T, Jiang Y, Dai J, Ma H, Zhou J, Wang Z, Hu Z, Ji G, Zhang Z, Shen H, Shi Y, Jin G. Exome Array Analysis Identifies Variants in SPOCD1 and BTN3A2 That Affect Risk for Gastric Cancer. Gastroenterology. 2017 Jun;152(8):2011-2021.
9. Jin G, Zhu M, Yin R, Shen W, Liu J, Sun J, Wang C, Dai J, Ma H, Wu C, Yin Z, Huang J, Higgs BW, Xu L, Yao Y, Christiani DC, Amos CI, Hu Z, Zhou B, Shi Y, Lin D, Shen H. Low-frequency coding variants at 6p21.33 and 20q11.21 are associated with lung cancer risk in Chinese populations. Am J Hum Genet. 2015 May;96(5):832-40.
10. Jin G, Ma H, Wu C, Dai J, Zhang R, Shi Y, Lu J, Miao X, Wang M, Zhou Y, Chen J, Li H, Pan S, Chu M, Lu F, Yu D, Jiang Y, Dong J, Hu L, Chen Y, Xu L, Shu Y, Pan S, Tan W, Zhou B, Lu D, Wu T, Zhang Z, Chen F, Wang X, Hu Z, Lin D, Shen H. Genetic variants at 6p21.1 and 7p15.3 are associated with risk of multiple cancers: evidence from three genome-wide association studies on different cancers in Han Chinese populations. Am J Hum Genet. 2012 Nov 2;91(5):928-34.