陈进，教授/博导，东南大学兼职博导，江苏特聘教授（卫生检验学），南京医科大学第三届“优秀研究生导师”(2022年)。2001、2006年毕业于南京大学获学士、博士; 2005年德国Tech. Univ. Munich，访问博士生，2006年Humboldt research fellow; 2009年日本自然科学研究院, postdoc，2010年研究助理教授；2014年到校工作。长期从事生物分析和分子伴侣研究工作，曾在大阪大学等合作交流，近年来发表SCI论文60多篇，被引1600余次。2015年获江苏特聘教授、校特聘教授，2016年入选江苏省双创团队，2017年入选省青年科技人才托举工程，2019年获校“优秀本科生导师”，2018-2023年获校“优秀指导教师”。
研究方向：1. 纳米技术和生物医学应用；2. 蛋白稳态和分子识别； 3. 肿瘤分子诊断与新型给药体系研究；4. 病原微生物检测和消杀。
课题组成员：
博士生：2020级: 蔡铃（东南大学联培，南医卫检）；阮红杰（临床联培，主任医师）
2021级：N. Ahmed（MPH，North South University）; 王昊（临床联培，主治医师）
2022级：乐冠楠（东南大学联培，南京农业大学动物医学）; 武亦娴（临床联培，主治医师）
硕士生：2020级: 裴巍（安医大卫检推免生）；邵雪梅（MPH, 南医卫检）；张李（MPH，安医大卫检）；朱馨怡（MPH，宁波大学预防）
2021级: 杨静（安医大卫检推免），国际MPH学生：Moussa（Mali）
2022级: 李雨晴（安医大卫检推免），李姮慧（MPH，重庆医大），贾晓宇（MPH，安医大）
2023级: 罗欢（西南医大预防推免）
长学制本科生：何佳铭；吴笑宇；陈鹏宇
已毕业学生：
硕士生：2019级: 周刘柱（南医卫检，苏州CDC），张嘉容（MPH，西南大学动物医学，浙江三甲医院）; 2018级: 朱萍（南医卫检，卫健委）；徐其兰（MPH，康达学院预防，上海CDC）；2017级：蔡铃 (转博)；2016级：宋翌琰（南医卫检，苏州医院）；2015级：徐智慧（南医卫检，苏州CDC）
博士生：2016级：俞心愉 (省血吸虫病防治研究所博士后)
国际MPH学生：2019级: Jeremiah (M.D., 长沙医学院)
博士后：R. Manikandan（PhD, University of Madras，印度）; 王军（博士，南京大学）
学术兼职：中国骆驼产业联盟专家委员会委员，江苏省生物医学工程协会专业委员会委员，AJPS, Burns & trauma, Eco Environ Health, Military Medical Research（国家卓越行动计划期刊）青年编委；《南京医科大学学报》青年编委，Chem. Eng. J., Anal. Chem.等50多种国际期刊审稿人。
本课题组每年招收2-4名博士/硕士研究生（学术或专业学位），常年招收博士后（除学校统招工资外，待遇面谈），欢迎具有医学（动物医学/病原微生物），生物分析/生物材料或蛋白质科学等相关专业背景学生加入。诚邀学者就相关课题探讨合作！
联系方式：南京市江宁区龙眠大道101号南京医科大学至诚楼；电话：025-86868248；邮箱：jchen@njmu.edu.cn
主要主持项目：
1. 国家自然科学基金联合基金（U1703118），新疆塔里木双峰驼血清免疫反应效应因子评价和结构生物学研究，2018-2020，主持，已结题。
2. 江苏省高等学校自然科学研究重大项目，基于我国双峰驼血清白蛋白的纳米载药应用研究，2019-2022，30万元，主持。
3. 江苏省自然科学基金面上项目，构建可控微纳体系发展肿瘤标志物多元检测新方法，2018-2021，10万元，主持，已结题。
4. 江苏省优势学科经费，2015-2022，100万元，主持。
5. 江苏省双创团队，2017-2020，300万元，Co-PI，已结题。
6. 江苏特聘教授基金（卫生检验学），2016-2019，100万元，主持，已结题。
7. 东南大学-南医大合作研究重点项目，2018-2021，30万元，主持，已结题。
近3年指导学生所获荣誉：
1. 研究生国家奖学金（2022年：裴巍，朱馨怡；2020年：朱萍，徐其兰；2019年：蔡铃；2018年：宋翌琰）；一等学业奖学金（15人次）；
东南大学博士学业奖学金：2021年，蔡铃（二等奖学金）
2. 大学生创新训练计划（国家级）2项（2020-2022年，19级临床/天元班；2017-2019年，15级卫检）；
大学生创新训练计划（省级）2项（2022-2024年，20级卫检；2023-2025年，22级临床/天元班）
3. 江苏省优秀硕士学位论文（2022年：徐其兰）；
校优秀硕士学位论文（2022年/朱萍，徐其兰；2021年/蔡铃；2020年/宋翌琰；2019年/徐智慧）
4. 南京医科大学学术之星硕士组（2022年：第6名/裴巍，第9名/朱馨怡；2020年第8名/朱萍；2018年第2名/宋翌琰）
5. 2023年第十八届“挑战杯”全国大学生课外学术科技作品竞赛黑科技专项赛 江苏省“恒星”级（省赛一等奖）1项（本科生）；“行星”级（省赛二等奖）1项（研究生）；
2021年第十七届“挑战杯”全国大学生课外学术科技作品竞赛黑科技专项赛国赛“恒星”奖（国赛一等奖）, 江苏省一等奖2项（本科生）；
2019年第十六届 “挑战杯”全国大学生课外学术科技作品竞赛江苏省二等奖（本科/研究生）
6. 校百佳研究生/优秀共青团员（2019年/蔡铃）；校研究生三好学生（2022年/朱馨怡，裴巍; 2021年/朱萍）
7. 校研究生优秀毕业生（2022年：裴巍，朱馨怡；2021年/朱萍、徐其兰；2020年/蔡铃；2019年/宋翌琰）
指导本科生以第一作者发表学术论文:
1. Shi Y#, Zhang C#, Jiang F#, Ruan H*, Chen J* et al. Electrospun antimicrobial polymeric nanofibers in wound dressings. Adv Polym Sci 2023, 291, 313. (IF=10.1)
2. 张萍（卫检）等, 基于功能化石墨烯的适配体生物传感器研究, 中国卫生检验杂志, 2016, 24, 3645.
近5年代表性论文：（#并列一作, *通讯）
42. Cai L#, Zhu X#, Ruan H#, Yang J, Wei W, Wu Y, Zhou L, Jiang H, Ji M, Chen J* Curcumin-stabilized silver nanoparticles encapsulated in biocompatible electrospun nanofibrous scaffold for sustained eradication of drug-resistant bacteria. Journal of Hazardous Materials, 2023, 452, 131290.
41. Zhang L#, Yang J#, Zhu X#, Jia X#, Liu Y, Cai L, Wu Y*, Ruan H*, Chen J* Electrospun nanofibrous membranes loaded with IR780 conjugated MoS2-nanosheet for dual-mode photodynamic/photothermal inactivation of drug-resistant bacteria. Environmental Technology & Innovation, 2023, 30, 103098.
40. Zhou L#, Zhu X#, Yang J#, Cai L, Zhang L, Jiang H, Ruan H*, Chen J* Deciphering photoactive species-directed antibacterial mechanism of bismuth oxychloride with nanoscale thickness-modulated photocatalytic activities. Journal of Environmental Management, 2023, 333, 117411.
39. Zhu X#, Li H#, Zhou L, Jiang H, Ji M, Chen J* Evaluation of the gut microbiome alterations in healthy rats after dietary exposure to different synthetic ZnO nanoparticles. Life Sciences, 2023, 312, 121250.
38. Zhu P#, Cai L#, Liu Q#, Feng S#, Ruan H, Zhang L, Zhou L, Jiang H, Wang H*, Wang J*, Chen J.* One-pot synthesis of α-Linolenic acid nanoemulsion-templated drug-loaded silica mesocomposites as efficient bactericide against drug-resistant Mycobacterium Tuberculosis. European Journal of Pharmaceutical Sciences, 2022, 176, 106261.
37. Yang X#, Wen X#, Dai J, Chen Y, Ding W, Wang J, Gu X, Zhang X, Chen J, Sutliff R, Emory S.*, Ruan G.* Probing the intracellular delivery of nanoparticles into hard-to-transfect cells. ACS Nano, 2022,16(6), 8751-8765.
36. Pei W#, Cai L#, Gong X#, Zhang L#, Zhang J, Zhu P, Jiang H, Wang C, Wang S.*, Chen J.* Drug-loaded oleic-acid grafted mesoporous silica nanoparticles conjugated with α-lactalbumin resembling BAMLET-like anticancer agent with improved biocompatibility and therapeutic efficacy. Materials Today Bio, 2022, 15, 100272.
35. Zhu X#, Wang J#, Cai L#, Wu Y#, Ji M, Jiang H, Chen J.* Dissection of antibacterial mechanism of zinc oxide nanoparticles with manipulable nanoscale morphologies. Journal of Hazardous Materials. 2022, 430, 128436.
34. Zhang J#, Xu Q#, Pei W#, Jiang H, Chen J.* Desolvation-induced formation of recombinant camel serum albumin-based nanocomposite for glutathione colorimetric determination. Sensors and Actuators B: Chemical, 2022, 357, 131417.
32. Wang J, Zhu X, Li C, Pei W, Cai L, Ni M, He J, Jiang H, Chen J.* Efficient exosome extraction through superparamagnetic iron oxides conjugation for the targeted delivery in rat brain. Materials today chemistry, 2022, 23, 100637.
32.Xu Q#, Zhang L#, Liu Y, Cai L, Zhou L, Jiang H, Chen J.* Encapsulating electrochemically generated MoS2 conjugated with chitosan oligosaccharide into electrospun nanofibrous scaffolds for improved near-infrared photothermal inactivation of bacteria. Journal of Nanostructure in Chemistry, 2022, 10.1007/s40097-022-00494-1.
31.Zhang J#, Xu Q#, Pei W#, Cai L, Yu X, Jiang H, Chen J.* Self-assembled recombinant camel serum albumin nanoparticles-encapsulated hemin with peroxidase-like activity for colorimetric detection of hydrogen peroxide and glucose. International Journal of Biological Macromolecules. 2021, 193, 2103-2112.
30.Wang J#, Zhu X#, Pei W#, Zhou L, Cai L, Jiang H, Chen J.* ZnO nanocluster loaded superparamagnetic iron oxide nanocomposites as recyclable antibacterial agent. Colloid and Interface Science Communications, 2021, 45, 100510.
29.Zhang J#, Sun H#, Pei W, Jiang H., Chen J.* Nanobody-based immunosensing methods for safeguarding public health. J Biomed Res. 2021, 35(4), 318-326.
28. Jiang Q#, Li D#, Liu Y, Mao Z, Yu Y, Zhu P, Xu Q, Sun Y, Hu L, Wang J, Chen J.*, Chen F*, Cao Y* Recyclable and green AuBPs@MoS2@tinfoil box for high throughput SERS tracking of diquat in complex compounds. Sensors and Actuators B: Chemical, 2021, 344, 130290.
27 Cai L#, Zhu P #, Huan F, Wang J, Zhou L, Jiang H, Ji M, Chen J.* Toxicity-attenuated mesoporous silica Schiff-base bonded anticancer drug complexes for chemotherapy of drug resistant cancer. Colloids Surf. B: Biointerfaces, 2021, 205, 111839.
26 Zhou L#, Cai L#, Zhang L, Wang J, Jiang H, Ruan H, Wu Y*, Feng S*, Chen J.* Electrospun chitosan oligosaccharide/polycaprolactone nanofibers loaded with wound-healing compounds as antibacterial dressings. International Journal of Biological Macromolecules. 2021, 183, 1145-1154.
25. Yang F#, Zhou L#, Dong X, Zhang W, Gao S, Wang X, Li L, Yu C, Wang Q, Yuan A, Chen J.* Visible-light-responsive nanofibrous α-Fe2O3 integrated FeOx cluster-templated siliceous microsheet for rapid catalytic phenol removal and enhanced antibacterial activity. ACS Appl. Mater. & Interfaces 2021, 13, 19803-19815.
24.Xu Q#, Liu Y#, Cai L#, Cao Y, Chen F, Zhou L, Zhu P, Jiang H, Jiang Q, Sun Y, Chen J.* A green electrolysis of silver-decorated MoS2 nanocomposite with an enhanced antibacterial effect and low cytotoxicity. Nanoscale Advances 2021, 3, 3460-3469.. (Front cover)
23. Zhu P#, Xu Z#, Cai L, Chen J.* Multifunctional porphyrin iron grafted mesoporous silica composites for drug delivery, dye degradation and colorimetric detection of hydrogen peroxide. Nanoscale Res. Lett. 2021, 16, 41.
22. Cai L#, Huang Y#, Duan Y#, Liu Q#, Xu Q, Jia J, Wang J, Tong Q, Luo P, Wen Y, Peng L, Wu Q, Hang X, Jiang H, Zhu P, Yang Y, Zhou B, Zeng L, Bi H*, Chen J.* Schiff-Base silver nanocomplexes formation on natural biopolymer coated mesoporous silica contributed to the improved curative effect on infectious microbes. Nano Research, 2021, 14, 2735-2748. (Back cover)
21. Song Y#, Zhu P#, Xu Z, Chen J.* Dual-responsive dual-drug loaded bioinspired polydopamine nanospheres as efficient therapeutic nanoplatform against drug-resistant cancer cells. ACS Appl. Bio Mater. 2020, 3, 5730-5740 (Back cover)
20. Yang F#*, Zhou L#, Gao S, Wang X, Chen J.*, Yuan A, Ang E* Combining two active states of FeOx in-situ in molecular sieve to deliver enhanced catalytic activity via creating special configuration and synergy. J. Alloys Comp., 2020, 844, 156137.
19. Song Y#, Cai L#, Tian Z, Wu Y*, Chen J.* Phytochemical curcumin co-formulated silver-decorated melanin-like polydopamine/mesoporous silica composite with improved antibacterial and chemotherapeutic effect against drug-resistant cancer cells. ACS Omega. 2020, 5, 15083-15094.
18. Yu X#, Xu Q#, Wu Y, Jiang H, Wei W, Zulipikaer A, Guo Y, Jirimutu, Chen J.* Nanobodies derived from Camelids represent versatile biomolecules for biomedical applications. Biomater. Sci., 2020, 8, 3559-3573. (Back cover)
17. Xu Q#, Zhu P#, Zhang J#, Liu Y, Cai L, Jiang H, Ji M, Chen J.* Electrochemical formation of distinct nanostructured MoS2 with altered antibacterial activity. Mater. Lett. 2020, 127809.
16. Zhu P#, Zhou L#, Song Y, Cai L, Ji M, Wang J, Ruan G, Chen J.* Encapsulating insoluble antifungal drugs into oleic acid-modified silica mesocomposites with enhanced fungicidal activity. J. Mater. Chem. B 2020, 8, 4899-4907.
15. Yu X#, Xu Z#, Wang X, Xu Q, Chen J.* Bactrian camel serum albumins-based nanocomposite as versatile biocargo for drug delivery, biocatalysis and detection of hydrogen peroxide. Mater. Sci. & Eng. C, 2020, 109, 110627.
14. Yu X#, Xieripu A#, Xu Q#, Song Y, Cai L, Chen J.* GSH-responsive curcumin/doxorubicin encapsulated Bactrian camel serum albumin nanocomposites with synergistic effect against lung cancer cells. J. Biomed Res., 2020, 34 (1), 54-66.
13. Yu X, Wu Y*, Zhang J, Jirimutu, Zulipikaer A, Chen J.* Pre-evaluation of Humoral Immune Response of Bactrian Camels by the Quantification of Th2 Cytokines using Real-time PCR. J. Biomed Res., 2020, 34(5), 387-394.
12. Cai L#, Qin X#, Xu Z, Song Y, Jiang H, Wu Y, Ruan H, Chen J.* Comparison of cytotoxicity evaluation of anticancer drugs between real-time cell analysis and CCK-8 method. ACS Omega. 2019, 4, 12036-12042.
11. Xu E, Yang H, Wu L*, Chen J, Wei W*, Liu Y, Liu S. Label-free poly(ADP-ribose) polymerase-1 activity assay based on perpendicular orientated mesoporous silica films. Sensor. Actuat. B: Chem. 2019, 294, 185-191.
10. Wang C.#, Li Y.#, Xu E., Zhou Q., Chen J., Wei W.*, Liu Y., Liu S. A label-free PFP-based photoelectrochemical biosensor for highly sensitive detection of PARP-1 activity. Biosens. Bioelectron., 2019, 138, 111308
9. Song Y.#, Zhu P.#, Wu Y.#, Tan L., Wei W., Liu S., Huang Q., Chen J.* Epsilon-poly-L-lysine decorated ordered mesoporous silica contributes to the synergistic antifungal effect and enhanced solubility of a lipophilic drug. Mater. Sci. & Eng. C, 2019, 99, 231-240.
8. Wei M.#, Wang C.#, Xu E., Chen J.*, Xu X., Wei W.*, Liu S. A simple and sensitive electrochemiluminescence aptasensor for determination of ochratoxin A based on a nicking endonuclease-powered DNA walking machine. Food Chem., 2019, 282, 141-146.
7. Xu Z.#, Cai L.#, Jiang H., Wen Y., Peng L., Wu Y., Chen J.* Real-time cell analysis of the cytotoxicity of a pH-responsive drug-delivery matrix based on mesoporous silica materials functionalized with ferrocenecarboxylic acid. Anal. Chim. Acta, 2019, 1051, 138-146.
6. Yang F.#, Song Y.#, Cai L.#, Zhou S., Chen J.*, Kong, Y.*. Enriched Ag nanospecies interspersed nanoporous siliceous antibacterial agent. ChemistrySelect 2018, 3(36), 10255-10258.
5. Liu Y.#, Xu X.#, Yang H., Xu E., Wu S., Wei W.*, Chen J.* Analysis of poly(ADP-ribose) polymerase-1 by enzyme-initiated auto-PARylation controlled aggregation of hemin-graphene nanocomposites. Analyst, 2018, 143, 2501-2507.
4. Xu Z.#, Song Y.#, Jiang H., Kong Y., Li X., Chen J.*, Wu Y.* Regeneration of arrayed gold microelectrodes equipped for a real-time cell analyzer. J. Vis. Exp., 2018, 133, e56250.
3. Song Y., Jiang H., Shi X., Chen J.*, Wu Y.*, Wei W.*, Detection of lead using a sensitive anodic stripping voltammetric method based on composite mesoporous silica/bismuth oxychloride modified electrode. ChemistrySelect, 2018, 3(8), 2423-2429.
2. Song Y., Jiang H., Wang B., Kong Y., Chen J.* Silver incorporated mussel-inspired polydopamine coatings on mesoporous silica as an efficient nanocatalyst and antimicrobial agent. ACS Appl. Mater. & Interfaces, 2018, 10, 1792-1801.
1. Song Y., Jiang H., Bi H.，Zhong G., Chen J.*, Wu Y.*, Wei W.* Multifunctional bismuth oxychloride/mesoporous silica composites for photocatalysis, anti-bacterial test and simultaneous stripping analysis of heavy metals. ACS Omega, 2018, 3, 973-981.