尤东方，女，博士，讲师，2016年获南京医科大学统计学(生物统计学方向)学士学位。2019.5-2020.7在哈佛大学公共卫生学院进行博士联合培养，导师：Prof. David C. Christiani。2021年获流行病与卫生统计学博士学位，导师：赵杨教授。
研究方向：
生物医学高维数据整合分析及因果推断方法研究、临床研究中的数据挖掘
联系方式：
邮箱：youdongfang@njmu.edu.cn
地址：南京医科大学龙眠大道101号至诚楼G402室
代表性论文：
Shao F#, Chen Y#, Xu H, Chen X, Zhou J, Wu Y, Tang Y, Wang Z, Zhang R, Lange T, Ma H, Hu Z, Shen H, Christiani DC, Chen F, Zhao Y*, You D*. Metabolic Obesity Phenotypes and Risk of Lung Cancer: A Prospective Cohort Study of 450,482 UK Biobank Participants. Nutrients. 2022 Aug 17;14(16):3370.
You D#, Wang D#, Wu Y#, Chen X, Shao F, Wei Y, Zhang R, Lange T, Ma H, Xu H, Hu Z, Christiani DC, Shen H, Chen F*, Zhao Y*. Associations of genetic risk, BMI trajectories, and the risk of non-small cell lung cancer: a population-based cohort study. BMC Med. 2022 Jun 6;20(1):203.
Tang Y#, You D#, Yi H#, Yang S*, Zhao Y*. IPRS: Leveraging Gene-Environment Interaction to Reconstruct Polygenic Risk Score. Front Genet. 2022 Mar 24;13:801397.
Wu Y#, Bai J#, Zhang M, Shao F, Yi H, You D*, Zhao Y*. Heterogeneity of Treatment Effects for Intensive Blood Pressure Therapy by Individual Components of FRS: An Unsupervised Data-Driven Subgroup Analysis in SPRINT and ACCORD. Front Cardiovasc Med. 2022 Feb 3;9:778756.
Zhou J#, Bai J#, Yue Y#, Chen X, Lange T, You D*, Zhao Y*. Association of Hypokalemia Incidence and Better Treatment Response in NSCLC Patients: A Meta-Analysis and Systematic Review on Anti-EGFR Targeted Therapy Clinical Trials. Front Oncol. 2022 Jan 5;11:757456.
Luan D#, You D#, Wu Y, Wu F, Xu Z, Li L, Jiao J, Zhang A, Feng H, Kong Y, Zhao Y*, Zhang Z*. Effects of interaction between single nucleotide polymorphisms and psychosocial factors on the response to antidepressant treatment in patients with major depressive disorder. J Genet Genomics. 2021 Dec 14:S1673-8527(21)00366-0.
You D#, Zhang M#, He W, Wang D, Yu Y, Yu Z, Lange T, Yang S, Wei Y, Ma H, Hu Z, Shen H, Chen F*, Zhao Y*. Association between dietary sodium, potassium intake and lung cancer risk: evidence from the prostate, lung, colorectal and ovarian cancer screening trial and the Women's Health Initiative. Transl Lung Cancer Res. 2021 Jan;10(1):45-56.
Chen X#, Gao W#, Li J#, You D#, Yu Z, Zhang M, Shao F, Wei Y, Zhang R, Lange T, Wang Q*, Chen F*, Lu X*, Zhao Y*. A predictive paradigm for COVID-19 prognosis based on the longitudinal measure of biomarkers. Brief Bioinform. 2021 Nov 5;22(6):bbab206.
You D#, Qin N#, Zhang M, Dai J, Du M, Wei Y, Zhang R, Hu Z, Christiani DC, Zhao Y*, Chen F*. Identification of genetic features associated with fine particulate matter (PM2.5) modulated DNA damage using improved random forest analysis. Gene. 2020 May 25;740:144570.
尤东方, 魏永越, 张汝阳, 陈峰, & 赵杨. (2018). 存在混杂时高维数据的随机森林分析. 南京医科大学学报：自然科学版, 38(7), 5.
#共同第一作者; *通讯作者.