黎书炜,医学博士,副教授,江苏省毒理学会青委会秘书长
研究方向:环境暴露与肿瘤
研究成果以第一作者/通讯作者身份在Nature Commun、Cell Rep Med、Cancer Res、Environ Sci Technol、Environ Int等权威期刊发表研究论文20余篇。主持国家自然科学基金青年项目、江苏省自然科学基金青年项目、江苏省高校自然科学研究面上项目、江苏省学位与研究生教育教学改革课题等。获第五届全省高校青年教师教学竞赛一等奖、全国毒理学教学竞赛一等奖、江苏省高校微课教学竞赛一等奖等。指导学生获江苏省大学生创新创业训练计划项目资助3项,中国毒理学会校园科普大赛三等奖、中国毒理学会校园科普大赛一、二等奖、江苏省研究生“医防融合,卫护健康”科研创新实践大赛二等奖、江苏省科普公益作品大赛二等奖等。
主持科研项目:
(1)国家自然科学基金青年,LncRNA MADT1基因m6A-SNP与结直肠癌发病风险及遗传学机制研究,82103915,主持
(2)江苏省自然科学基金青年项目,m6A修饰区域遗传变异调控lncRNA-877参与结直肠癌发生的机制研究,BK20210535,主持
(3)江苏省高校自然科学研究面上项目,性激素及其通路基因遗传变异与结直肠癌易感的关联研究,20KJB330008,主持
教学获奖:
(1)第五届全省高校青年教师教学竞赛一等奖
(2)全国毒理学教学竞赛一等奖
(3)江苏省高校微课教学竞赛一等奖
(4)南京医科大学教师教学创新大赛特等奖
(5)南京医科大学课程思政教学创新大赛特等奖
代表性论著:
(1) Shuwei Li#; Shenya Xu#; Yehua Chen; Jieyu Zhou; Shuai Ben; Mengfan Guo; Haiyan Chu; Dongying Gu; Zhengdong Zhang; Meilin Wang*; Metal Exposure Promotes Colorectal Tumorigenesis via the Aberrant N6-Methyladenosine Modification of ATP13A3, Environmental Science & Technology, 2023, 57(7): 2864-2876
(2) Shuwei Li#; Mulong Du#; Kaili Xu; Shuai Ben; Tianru Zhu; Mengfan Guo; Junyi Xin; Lingjun Zhu; Dongying Gu; Zhengdong Zhang; Meilin Wang*; Genetic Modulation of BET1L Confers Colorectal Cancer Susceptibility by Reducing miRNA Binding and m6A Modification, Cancer Research, 2023, 83(13): 2142-2154
(3) Shuwei Li#; Yehua Chen#; Lisheng Xie#; Yixuan Meng; Lingjun Zhu; Haiyan Chu; Dongying Gu; Zhengdong Zhang; Mulong Du; Meilin Wang*; Sex hormones and genetic variants in hormone metabolic pathways associated with the risk of colorectal cancer, Environment International, 2020, 137:105543
(4) Shuwei Li#; Kaili Xu#; Dongying Gu#; Lei He; Lisheng Xie; Zhengxin Chen; Zhimin Fan; Lingjun Zhu 6; Mulong Du; Haiyan Chu; Zhengdong Zhang; Yuan Wu*; Min Ni*; Meilin Wang*. Genetic variants in RPA1 associated with the response to oxaliplatin-based chemotherapy in colorectal cancer, Journal of Gastroenterology, 2019 Nov;54(11):939-949
(5) Hengyang Shen#; Yang Chen#; Menghuan Xu#; Jieyu Zhou; Changzhi Huang; Zhenling Wang; Yu Shao; Hongqiang Zhang; Yunfei Lu; Shuwei Li*; Zan Fu*; Cellular senescence gene TACC3 associated with colorectal cancer risk via genetic and DNA methylated alteration, Archives of Toxicology,2024 May;98(5):1499-1513
(6) Junyi Xin#, Dongying Gu#, Shuwei Li#, Sangni Qian#, Yifei Cheng, Wei Shao, Shuai Ben, Silu Chen, Linjun Zhu, Mingjuan Jin, Kun Chen, Zhibin Hu, Zhengdong Zhang, Mulong Du, Hongbing Shen, Meilin Wang*. Integration of pathologic characteristics, genetic risk and lifestyle exposure for colorectal cancer survival assessment. Nature Communications. 2024 Apr 8;15(1):3042
(7) Bingxin Liu#; Shuwei Li#; Yifei Cheng#; Peng Song; Menghuan Xu; Zhengyi Li; Wei Shao; Junyi Xin; Zan Fu; Dongying Gu; Mulong Du; Zhengdong Zhang; Meilin Wang*. Distinctive multicellular immunosuppressive hubs confer different intervention strategies for left- and right-sided colon cancers. Cell Reports Medicine. 2024. Online, 101589
(8) Shuai Ben#; Shuwei Li#; Dongying Gu#; Lingyan Zhao; Shenya Xu; Zhutao Ding; Silu Chen; Yifei Cheng; Junyi Xin; Mulong Du; Meilin Wang*; Benzo[a]pyrene exposure affects colorectal cancer susceptibility by regulating ERβ-mediated LINC02977 transcription, Environment International, 2024, 184: 108443