胡志斌,博士,二级教授,博士生导师。现担任南京医科大学校长,南京医科大学生殖医学国家重点实验室主任。国家自然科学基金杰出青年基金获得者,国务院政府特殊津贴专家,教育部长江学者特聘教授,科技部中青年科技创新领军人才,国家百千万工程人才,树兰医学青年奖获得者。1997年至2002年就读于南京医科大学临床医学系,2007年获得南京医科大学流行病与卫生统计学博士学位并留校任教,2005年至2007年在美国德州大学安德森癌症中心流行病学系从事博士后研究,2009年在德国癌症研究中心分子流行病系从事访问学者研究,2010年起担任南京医科大学流行病学与卫生统计学系教授。长期致力于复杂疾病的分子流行病学研究,在Nat Genet、Cell Research、Hepatology、Nat Commun、 J Clin Oncol等国际知名杂志上发表研究论文300余篇,SCI他引10000余次,连续入选2014-2019年度Elsevier中国高被引学者。先后获国家杰出青年基金、青年973、国家自然科学基金重点项目、国家自然科学基金重大项目课题、国家重点研发计划项目等项目的资助。以主要完成人获国家自然科学二等奖2项(第3)、国家科技进步奖二等奖1项(第6)及部省级科技进步一等奖6项。担任中国生理学会生殖科学专业委员会副主任委员、中国抗癌协会第一届青年理事会常务副理事长、中华预防医学会流行病分会青年委员会副主任委员等。受邀担任Cancer Medicine 杂志副主编及Gene等多个国际杂志编委。
研究方向:复杂疾病的分子遗传流行病学
联系方式:
地址:南京市江宁区龙眠大道101号
电话:025-86868440
主要在研项目:
1. 国家自然科学基金重点项目(No. 31530047),蛋白磷酸化在人类精子发生过程中的作用机制,2016/01-2020/12,主持
2. 国家自然科学基金重点项目(No. 81830100),基于出生队列的先天性心脏病多因素病因研究,2019/01-2023/12,主持
3. 国家重点研发计划项目(No. 2018YFC1004200),不孕不育人群环境与遗传致病因子鉴定及交互作用研究,2018/12-2021/12,主持
代表性论文:
1. Cheng Wang†, Hong Lv†, Xiufeng Ling†, Hong Li†, Feiyang Diao†, Juncheng Dai, Jiangbo Du, Ting Chen, Qi Xi, Yang Zhao, Kun Zhou, Bo Xu, Xiumei Han, Xiaoyu Liu, Meijuan Peng, Congcong Chen, Shiyao Tao, Lei Huang, Cong Liu, Mingyang Wen, Yangqian Jiang, Tao Jiang, Chuncheng Lu, Wei Wu, Di Wu, Minjian Chen, Yuan Lin, Xuejiang Guo, Ran Huo, Jiayin Liu, Hongxia Ma, Guangfu Jin, Yankai Xia, Jiahao Sha, Hongbing Shen*, Zhibin Hu*. Association of assisted reproductive technology, germline de novo mutations and congenital heart defects in a prospective birth cohort study.Cell Res. 2021 Aug;31(8):919-928. (通讯作者)
2. Zhu M†, Wang T†, Huang Y, Zhao X, Ding Y, Zhu M, Ji M, Wang C, Dai J, Yin R, Xu L, Ma H, Wei Q, Jin G*, Hu Z*, Shen H*. Genetic Risk for Overall Cancer and the Benefit of Adherence to a Healthy Lifestyle. Cancer Res. 2021 Sep;81(17):4618-4627. (并列通讯作者)
3. Ci Song†, Yan Xu†, Yuqing Ding†, Yanfang Zhang, Na Liu, Lin Li, Zhun Li, Jiangbo Du, Hua You, Hongxia Ma, Guangfu Jin, Xudong Wang, Hongbing Shen, Yuan Lin*, Xiaoqing Jiang*, Zhibin Hu*. The rates and medical necessity of cesarean delivery in China, 2012-2019: an inspiration from Jiangsu. BMC Med. 2021 Jan 25;19(1):14. (通讯作者)
4. Hong Lv†, Feiyang Diao†, Jiangbo Du†, Ting Chen†, Qingxia Meng†, Xiufeng Ling, Hong Li, Ci Song, Qi Xi, Yangqian Jiang, Yan Xu, Shiyao Tao, Lei Huang, Mingyang Wen, Meijuan Peng, Cong Liu, Qun Lu, Yuanlin He, Yin Yin, Xiaoyu Liu, Bo Xu, Xiumei Han, Kun Zhou, Tao Jiang, Yang Zhao, Hongxia Ma, Guangfu Jin, Yankai Xia, Jiayin Liu, Yuan Lin*, Zhibin Hu*, Hongbing Shen*. Assisted reproductive technology and birth defects in a Chinese birth cohort study. Lancet Reg Health West Pac. 2021 Jan 22;7:100090. (并列通讯作者)
5. Wang C†, Gu Y†, Zhang E†, Zhang K, Qin N, Dai J, Zhu M, Liu J, Xie K, Jiang Y, Guo X, Liu M, Jin G, Ma H, Jiang T, Yin R, Xia Y, Liu L, Wang S, Shen B, Huo R, Xu L, Sha J, Qu B, Shen H*,Hu Z*.A cancer-testis non-coding RNA LIN28B-AS1 activates driver gene LIN28B by interacting with IGF2BP1 in lung adenocarcinoma.Oncogene. 2019 Mar;38(10):1611-1624. (通讯作者)
6. Wang C†, Gu Y†, Zhang K†, Xie K†, Zhu M, Dai N, Jiang Y, Guo X, Liu M, Dai J, Wu L, Jin G, Ma H, Jiang T, Yin R, Xia Y, Liu L, Wang S, Shen B, Huo R, Wang Q, Xu L, Yang L, Huang X, Shen H*, Sha J*, Hu Z*. Systematic identification of genes with a cancer-testis expression pattern in 19 cancer types. Nat Commun.2016 Jan 27,7:10499. (通讯作者)
7. Lin Y†, Guo X†, Zhao B†, Liu J†, Da M†, Wen Y, Hu Y, Ni B, Zhang K, Yang S, Xu J, Dai J, Wang X, Xia Y, Ma H, Jin G, Yu S, Liu J, Keavney BD, Goodship JA, Cordell HJ, Wang X, Shen H, Sha J, Zhou Z, Chen Y, Mo X*, Luo L*, Hu Z*. Association analysis identifies new risk loci for congenital heart disease in Chinese populations. Nat Commun. 2015 Aug 18;6:8082. (通讯作者)
8. Hu Z†*, Li Z†, Yu J†, Tong C†, Lin Y†, Guo X†, Lu F, Dong J, Xia Y, Wen Y, Wu H, Li H, Zhu Y, Ping P, Chen X, Dai J, Jiang Y, Pan S, Xu P, Luo K, Du Q, Yao B, Liang M, Gui Y, Weng N, Lu H, Wang Z, Zhang F, Zhu X, Yang X, Zhang Z, Zhao H, Xiong C, Ma H, Jin G, Chen F, Xu J, Wang X, Zhou Z, Chen ZJ*, Liu J*, Shen H, Sha J*. Association analysis identifies new risk loci for non-obstructive azoospermia in Chinese men. Nat Commun. 2014 May 23;5:3857. (第一作者及通讯作者)
9. Hu Z†*, Shi Y†, Mo X†, Xu J†, Zhao B†, Lin Y†, Yang S, Xu Z, Dai J, Pan S, Da M, Wang X, Qian B, Wen Y, Wen J, Xing J, Guo X, Xia Y, Ma H, Jin G, Yu S, Liu J, Zhou Z*, Wang X, Chen Y*, Sha J, Shen H*.A genome-wide association study identifies two risk loci for congenital heart malformations in Han Chinese populations. Nat Genet. 2013 Jul;45(7):818-21.(第一作者及并列通讯作者)
10. Hu Z†* , Liu Y†, Zhai X†, Dai J†, Jin G†, Wang L†, Zhu L, Yang Y, Liu J, Chu M, Wen J, Xie K, Du G, Wang Q, Zhou Y, Cao M, Liu L, He Y, Wang Y, Zhou G, Jia W, Lu J, Li S, Liu J, Yang H, Shi Y*, Zhou W*, Shen H*. New loci associated with chronic hepatitis B virus infection in Han Chinese. Nat Genet. 2013 Dec;45(12):1499-503. (第一作者及并列通讯作者)
11. Jin G†, Ma H†, Wu C†, Dai J, Zhang R, Shi Y, Lu J, Miao X, Wang M, Zhou Y, Chen J, Li H, Pan S, Chu M, Lu F, Yu D, Jiang Y, Dong J, Hu L, Chen Y, Xu L, Shu Y, Pan S, Tan W, Zhou B, Lu D, Wu T, Zhang Z, Chen F, Wang X, Hu Z*, Lin D*, Shen H. Genetic variants at 6p21.1 and 7p15.3 are associated with risk of multiple cancers in Han Chinese. Am J Hum Genet. 2012 Nov 2;91(5):928-34. (通讯作者)
12. Hu L†, Zhai X†, Liu J†, Chu M, Pan S, Jiang J, Zhang Y, Wang H, Chen J, Shen H, Hu Z*. Genetic variants in human leukocyte antigen/DP-DQ influence both hepatitis B virus clearance and hepatocellular carcinoma development. Hepatology. 2012 May;55(5):1426-31. (通讯作者)
13. Dong J†, Hu Z†, Wu C†, Guo H, Zhou B, Lv J, Lu D, Chen K, Shi Y, Chu M, Wang C, Zhang R, Dai J, Jiang Y, Cao S, Qin Z, Yu D, Ma H, Jin G, Gong J, Sun C, Zhao X, Yin Z, Yang L, Li Z, Deng Q, Wang J, Wu W, Zheng H, Zhou G, Chen H, Guan P, Peng Z, Chen Y, Shu Y, Xu L, Liu X, Liu L, Xu P, Han B, Bai C, Zhao Y, Zhang H, Yan Y, Amos CI, Chen F, Tan W, Jin L, Wu T, Lin D, Shen H*. Association analyses identify multiple new lung cancer susceptibility loci and their interactions with smoking in the Chinese population. Nat Genet, 2012 Jul 15; 44(8):895-9. (并列第一作者)
14. Hu Z†, Xia Y†, Guo X†, Dai J, Li H, Hu H, Jiang Y, Lu F, Wu Y, Yang X, Li H, Yao B, Lu C, Xiong C, Li Z, Gui Y, Liu J, Zhou Z, Shen H*, Wang X*, Sha J*. A genome-wide association study in Chinese men identifies three risk loci for non-obstructive azoospermia. Nat Genet. 2011 Dec 25;44(2):183-6. (第一作者)
15.Hu Z†, Wu C, Shi Y, Guo H, Zhao X, Yin Z, Yang L, Dai J, Hu L, Tan W, Li Z, Deng Q, Wang J, Wu W, Jin G, Jiang Y, Yu D, Zhou G, Chen H, Guan P, Chen Y, Shu Y, Xu L, Liu X, Liu L, Xu P, Han B, Bai C, Zhao Y, Zhang H, Yan Y, Ma H, Chen J, Chu M, Lu F, Zhang Z, Chen F, Wang X, Jin L, Lu J, Zhou B, Lu D, Wu T, Lin D, Shen H*. A genome-wide association study identifies two new lung cancer susceptibility loci at 13q12.12 and 22q12.2 in Han Chinese. Nat Genet, 2011 Jul 3;43(8):792-6. (第一作者)