Professor of Nutrition and Food Hygiene,
School of Public Health, Nanjing Medical University
Lz-ny@njmu.edu.cn
13851987731
李忠,博士,教授
Zhong Li, Ph.D
Research Interest
Phytoestrogens and estrogen-dependent disease
Phytochemicals and metastasis, angiogenesis of human cancer
Education
Visiting Scholar. Department of Food Science & Human Nutrition, University of Illinois at Urbana-Champaign. IL, USA, 2003-2005
Ph.D in Food Science, 1998, Huazhong Agricultural University. Wuhan, Hubei, PR China
M.Sc in Food Science, 1995, Huazhong Agricultural University. Wuhan, Hubei, PR China
B.Sc in Food Science, 1990, Huazhong Agricultural University. Wuhan, Hubei, PR China
Honors and Awards
2010 Outstanding and Excellent Teacher Award of Nanjing Medical University
2008 Middle-aged and Young Science Leaders of Colleges and Universities of Jiangsu Province
Ongoing Research Projects
l PI, The effects of ROS-dependent epigenetic silencing of RECK on 27-Hydroxycholesterol- induced invasion and metastasis in human breast cancer. NSFC, 81673205
l PI, The mechanism of arsenic increase Chemotherapy sensitivity in Hepatocellular Carcinoma. the Major Program of Natural Science Research of Jiangsu Higher Education Institutions, 15KJA330001
Selected Papers
1. Resveratrol Alleviates 27-Hydroxycholesterol-Induced Senescence in Nerve Cells and Affects Zebrafish Locomotor Behavior via Activation of SIRT1-Mediated STAT3 Signaling. Oxid Med Cell Longev. 2021, 6673343. doi: 10.1155/2021/6673343. eCollection 2021.
2. The 14-3-3η/GSK-3β/β-catenin complex regulates EndMT induced by 27-hydroxycholesterol in HUVECs and promotes the migration of breast cancer cells. Cell Biol Toxicol. 2021, 37(4):515-529
3. 27-hydroxycholesterol-induced EndMT acts via STAT3 signaling to promote breast cancer cell migration by altering the tumor microenvironment. Cancer Biol & Med. 2020, 17:88-100