Li Xiaoting

发布者:公共卫生学院发布时间:2022-10-25浏览次数:493

  

Curriculum Vitae

Xiaoting Li, Ph.D. 

Associated professor of Nutrition and Food Safety

Tel: +86-25-86868329

E-mail: xiaotingli@njmu.edu.cn  


Research Interest

Nutrients and Cancer   


Education

Anhui Medical University, Preventive Medicine, B.S. (2003.10-2008.7)

Nanjing Medical University, Nutrition and Food Safety, M.S. (2008.9-2011.7)

Nanjing Medical University, Nutrition and Food Safety, Ph.D. (2011.9-2014.7)


Research Projects

PI, Regulation of ΔNp63α/Notch Axis in Cigarette Smoke-induced Transformation of Normal Human Bronchial Epithelial Cells to Lung Cancer Stem Cells and Sulforaphane Intervention. National Natural Science Foundation of China, # 81602839, 2017.1-2019.12

PI, Sulforaphane inhibited Cigarette Smoke-induced Lung Cancer Stem Cells via ΔNp63α Suppression. Natural Science Foundation of Jiangsu Provence, # BK20161029, 2016.7-2019.6

PI, Role of TP63α/miR-19 in Regulating EMT of Non-small Cell Lung Cancer and Curcumin Intervention. Key Project of Science and Technology Development Fund of Nanjing Medical University, # 2015NJMUZD020, 2016.1-2017.12


Selected Papers ( # co-first author; * co-corresponding author)

  • Xie C, Zhu J, Huang C, Yang X, Wang X, Meng Y, Geng S, Wu J, Shen H, Hu Z, Meng Z*, Li X*, Zhong C*. Interleukin-17A mediates tobacco smoke-induced lung cancer epithelial-mesenchymal transition through transcriptional regulation of ΔNp63α on miR-19. Cell Biol Toxicol. 2022;38(2):273-289.

  • Xie C, Zhu J, Yang X, Huang C, Zhou L, Meng Z*, Li X*, Zhong C*. TAp63α Is Involved in Tobacco Smoke-Induced Lung Cancer EMT and the Anti-cancer Activity of Curcumin via miR-19 Transcriptional Suppression. Front Cell Dev Biol. 2021;9:645402.

  • Xie C, Ge M, Jin J, Xu H, Mao L, Geng S, Wu J, Zhu J*, Li X*, Zhong C*. Mechanism investigation on Bisphenol S-induced oxidative stress and inflammation in murine RAW264.7 cells: The role of NLRP3 inflammasome, TLR4, Nrf2 and MAPK. J Hazard Mater 2020;394:122549.

  • Xie C, Zhu J, Jiang Y, Chen J, Wang X, Geng S, Wu J, Zhong C*, Li X*, Meng Z*. Sulforaphane Inhibits the Acquisition of Tobacco Smoke-Induced Lung Cancer Stem Cell-Like Properties via the IL-6/ΔNp63α/Notch Axis. Theranostics. 2019;9(16):4827-4840. 

  • Xie C, Zhu J, Wang X, Chen J, Geng S, Wu J, Zhong C*, Li X*. Tobacco smoke induced hepatic cancer stem cell-like properties through IL-33/p38 pathway. J Exp Clin Cancer Res. 2019;38(1):39. 

  • Wang J, Chen J, Jiang Y, Shi Y, Zhu J, Xie C, Geng S, Wu J, Zhang Q, Wang X, Meng Y, Li Y, Chen Y, Cao W, Wang X, Zhong C*, Li X*. Wnt/β-catenin modulates chronic tobacco smoke exposure-induced acquisition of pulmonary cancer stem cell properties and diallyl trisulfide intervention. Toxicol Lett. 2018;291:70-76.