沈思鹏, 博士副教授
Sipeng Shen, PhD
Associate Professor of Biostatistics
Research Interest
Strategiesand methods of high-dimensional multi-omics data integration
Deep datamining in cancer research
Education
DATE | INSTITUTION | DISCIPLINE | DEGREE |
2014.9-2019.6 | Nanjing Medical University | Epidemiology and Biostatistics | Ph.D. |
2009.9-2014.6 | Nanjing Medical University | Preventive Medicine | MBBS |
Academictraining
DATE | INSTITUTION | POSITION |
2017.03-2019.03 | HarvardT. H. Chan School of Public Health | Visiting Scientist (Advisor:David C. Christiani) |
Ongoing Research Projects
PI,Cross-omics integrated statistical methodology research based on genetic variation in lung cancer risk. NSFC, 82103946.
Selected Papers
1.Shen S#,Zhang R#,Jiang Y, Li Y, Lin L, Liu Z, Zhao Y, Shen H, Hu Z, Wei Y*,Chen F*.Comprehensive analyses of m6A regulators and interactive coding andnon-coding RNAs across 32 cancer types. MolecularCancer. 2021Apr 13;20(1):67.
2.Shen S#,Wei Y#,Li Y, Duan W, Dong X, Lin L, You D, Tardon A, Chen C, Field J, HungR, Liu G, Zhu D, Amos C, Su L, Zhao Y, Hu Z, Shen H, Zhang R*,Chen F*,Christiani DC*.A multi-omics study links TNS3 and SEPT7 to long-term former smokingNSCLC survival. npjPrecision Oncology. 2021May 17;5(1):39.
3.Shen S#,Wang G#,Zhang R, Zhao Y, Wei Y, Chen F*.Development and validation of an immune gene-set based prognosticsignature in ovarian cancer. EBioMedicine.2019;40:318-26.
4.Shen S#,Zhang R#,Guo Y, Loehrer E, Wei Y, Zhu Y, Yuan Q, Moran S, Fleischer T,Bjaanaes MM, Karlsson A, Planck M, Staaf J, Helland A, Esteller M, SuL, Chen F*,Christiani DC*.A multi-omic study reveals BTG2 as a reliable prognostic marker forearly-stage non-small cell lung cancer. Molecularoncology.2018;12(6):913-24.
5.Shen S#,Zhang R#,Zhang J, Wei Y, Guo Y, Su L, Chen F, Christiani DC*.Welding fume exposure is associated with inflammation: a globalmetabolomics profiling study. EnvironmentalHealth.2018 Dec;17(1):68.
6.Shen S, Wang G, Shi Q, Zhang R, Zhao Y, Wei Y*,Chen F*,Christiani DC. Seven-CpG-based prognostic signature coupled with geneexpression predicts survival of oral squamous cellcarcinoma. ClinicalEpigenetics.2017 Aug 24;9(1):88.
7. ZhangR#, ShenS#,Wei Y#,Zhu Y, Li Y, Chen J, Guan J, Pan Z, Wang Y, Zhu M, Xie J, Xiao X, ZhuD, Li Y, Albanes D, Landi MT, Caporaso N, Lam S, Tardon A, Chen C,Bojesen SE, Johansson M, Risch A, Bickeboller H, Wichmann HE, RennertG, Arnold S, Brennan P, McKay J, Field JK, Shete SS, Le Marchand L,Liu G, Andrew A, Kiemeney LA, Zienolddiny-Narui S, Behndig A,Johansson M, Cox A, Lazarus P, Schabath MB, Aldrich MC, Dai J, Ma H,Zhao Y, Hu Z, Hung RJ, Amos CI, Shen H, Chen F*,Christiani DC. A large-scale genome-wide gene-gene interaction studyof lung cancer susceptibility in Europeans with a trans-ethnicvalidation in Asians. JThorac Oncol. 2022.
8. ChenJ#, ShenS#, LiY#,Fan J, Xiong S, Xu J, Zhu C, Lin L, Dong X, Duan W, Zhao Y, Qian X,Liu Z, Wei Y, Christiani DC*, ZhangR*,Chen F*.APOLLO: An accurate and independently validated prediction model oflower-grade gliomas overall survival and a comparative study ofmodel performance. EBioMedicine.2022;79:104007.
9.Shen S#,Bai J#,Wei Y, Wang G, Li Q, Zhang R, Duan W, Yang S, Du M, Zhao Y,Christiani DC, Chen F*.A seven-gene prognostic signature for rapid determination of head andneck squamous cell carcinoma survival. Oncologyreports.2017 Dec 1;38(6):3403-11.
10.Wang, F. #,Tan, F. #,Shen, S.#, Wu, Z.#, Cao, W.#, Yu, Y.,Dong, X., Xia, C., Tang, W., Xu, Y., Qin, C., Zhu, M., Li, J., Yang,Z., Zheng, Y., Luo, Z., Zhao, L., Li, J., Ren, J., Shi, J., Huang,Y., Wu, N., Shen, H., Chen, W., Li, N.*& He, J*.A Risk-Stratifieed Approach for Never- and Ever-Smokers in LungCancer Screening: A Prospective Cohort Study in China. AmJ Respir Crit Care Med,doi:10.1164/rccm.202204-0727OC (2022).
