Professor of Occupational and Environmental Health
倪春辉，博士，教授
Chunhui Ni，MD,PhD
Research Interest
Mechanisms of Occupational Pulmonary Fibrosis
Epidemiology of Occupational Exposure and Health
Education
Xinjiang Medical College, Preventive Medicine, B.S. (1978.9-1983.7)
Xian Medical College, Occupational Health, M.S. (1985.9-1988.7)
Nanjing Medical University, Occupational Health, Ph.D. (2005.9-2009.12)
The University of Birmingham, UK, Institute of Occupational Health , Research Fellow (1995.1-1996.5)
Ongoing Research Projects
1. PI, The Mechanisms of PVT1-related non-coding RNA in Regulating Silica-induced Pulmonary Fibrosis. NSFC, 82073518
2. PI, LncRNA-ATB promotes EMT during silica-induced pulmonary fibrosis by sponging miR-200c and miR-34c-3p. NSFC, 81874258
Selected Papers
1. Wenqing Sun, Yan Li, Dongyu Ma, Yi Liu, Qi Xu, Demin Cheng, Guanru Li, Chunhui Ni. ALKBH5 promotes lung fibroblast activation and silica-induced pulmonary fibrosis through miR-320a-3p and FOXM1. Cellular & Molecular biology letters,2022,27(1)：26
2. Weiwen Yan, Dongyu Ma , Yi Liu, Wenqing Sun , Demin Cheng, Guanru Li, Siyun Zhou , Yue Wang, Huanqiang Wang , Chunhui Ni. PTX3 alleviates hard metal-induced lung injury through potentiating efferocytosis. Ecotoxicology and Environmental Safety, 2022,230:113139
3. Jiali Yuan, Ting Wang, Lijuan Wang, Ping Li, Meng Zhu, Hongbin Shen, Chunhui Ni. Transcriptome-wide association study identifies PSMB9 as a susceptibility gene for coal workers’ pneumoconiosis in a Chinese population. Environmental Toxicology，2022 :235544
4. Huanqiang Wang, Siyun Zhou, Yi Liu , Yihan Yu, Sha Xu, Lan Peng, Chunhui Ni. Exploration study on serum metabolic profiles of Chinese male patients with artificial stone silicosis, silicosis, and coal worker's pneumoconiosis. Toxicology Letter, 2021,356:132-142
5. Demin Cheng, Qi Xu, Yue Wang Guanru Li, Wenqing Sun, Dongyu Ma, Siyun Zhou, Yi Liu, Lei Han, Chunhui Ni. Metformin attenuates silica-induced pulmonary fibrosis via AMPK signaling. Journal of Translational Medicine, 2021.19:349
6. Qi Xu, Demin Cheng, Yi Liu, Honghong Pan, Guanru Li, Ping Li, Yan li, Wenqing Sun, Dongyu Ma, Chunhui Ni. LncRNA ATB regulates epithelial-mesenchymal transition progression in pulmonary fibrosis via sponging miR-29b-2-5p and miR-34c-3p. J Cell Mol Med,2021,00:1-13
7. Jiali Yuan, Ping Li, Honghong Pan, Qi Xu, Tiantian Xu, Yan Li, Dong Wei , Jingyu Chen, Chunhui Ni. miR-770-5p inhibits the activation of pulmonary fibroblasts and silica-induced pulmonary fibrosis through targeting TGFBR1. Ecotoxicology and Environmental Safety, 2021,220:112372
8. Qi Xu, Demin Cheng, Guanru Li, Yi Liu, Ping Li, Wenqing Sun, Dongyu Ma, Chunhui Ni. CircHIPK3 regulates pulmonary fibrosis by facilitating glycolysis in miR-30a-3p/FOXK2-dependent manner. International Journal of Biological Sciences, 2021,17(9):2294-2307
9. Yan Li, Wenqing Sun, Honghong Pan, Jiali Yuan, Qi Xu, Tiantian Xu, Ping Li, Demin Cheng, Yi Liu, Chunhui Ni. LncRNA-PVT1 activates lung fibroblasts via miR-497-5p and is facilitated by FOXM1. Ecotoxicology and Environmental Safety,2021,213:112030
10. Demin Cheng, Qi Xu, Yi Liu, Guanru Li, Wenqing Sun, Dongyu Ma, Chunhui Ni. Long noncoding RNA-SNHG20 promotes silica-induced pulmonary fibrosis by miR-490-3p/TGFBR1 axis. Toxicology 2021,451(3):152683
11. Ting Wang, Wenqing Sun, Hongyan Wu, Yuxin Cheng, Yan Li, Fanqing Meng, Chunhui Ni. Respiratory traits and coal workers' pneumoconiosis: mendelian randomization and association analysis. Occupational and Environmental Medicine.2021,78：137-141
