Associate professor of Occupational Medical and Environmental Health, Nanjing Medical University
ruizheng@njmu.edu.cn
郑瑞，博士，副教授
RuiZHENG, MD, PhD
RESEARCHINTEREST
Environmental pollution and exposure, Complex disorder, Epigenetic,Exosomes
EDUCATION
Nanjing Medical University, Preventive Medicine, B.S.(2010/09-2015/06)
Nanjing Medical University, Occupational and Environmental Health, Ph.D.(2015/09-2020/06)
National Institute of Environmental Health Sciences (NIEHS), Biostatistics &Computational Biology, Visiting Fellow. (2019/06-2019/10)
Nanjing Medical University, Occupational and Environmental Health,Postdoctoral Fellow. (2020/07-2022/07)
OngoingResearch Projects
PI, The mechanism study of tumor-associated macrophages-derived exosomallncRNA BCHET involved in the malignant progression of bladder cancerpromoted by smoking, NSFC, 82103878
PI, The mechanism study and biomarkers of malignant progression of bladdercancer induced by tobacco smoke exposure, Fundamental Science General Program in Jiangsu Higher Education Institutions (NaturalScience), 21KJB330002
SelectedPapers
ZhengR, Du M, Tian M, ZhuZ, Wei C, Chu H, Gan C, Liang J, Xue R, Gao F, Mao Z, Wang M, ZhangZ. Fine Particulate Matter Induces Childhood Asthma Attacks viaExtracellular Vesicle-Packaged Let-7i-5p-Mediated Modulation of theMAPK Signaling Pathway. Adv Sci (Weinh). 2022 Jan;9(3):e2102460.
ZhengR, Zhang K, Tan S,Gao F, Zhang Y, Xu W, Wang H, Gu D, Zhu L, Li S, Chu H, Zhang Z, LiuL, Du M, Wang M. Exosomal circLPAR1 functions in colorectal cancerdiagnosis and tumorigenesis through suppressing BRD4 viaMETTL3-eIF3h interaction. Mol Cancer. 2022 Feb 14;21(1):49.
ZhengR, Du M, Ge Y, Gao F,Xin J, Lv Q, Qin C, Zhu Y, Gu C, Wang M, Zhu Q, Guo Z, Ben S, Chu H,Ye D, Zhang Z, Wang M. Identification of low-frequency variants ofUGT1A3 associated with bladder cancer risk by next-generationsequencing. Oncogene. 2021 Apr;40(13):2382-2394.
ZhengR, Liang J, Lu F, LiS, Zhang G, Wang X, Liu M, Wang W, Chu H, Tao G, Zhao Q, Wang M, DuM, Qiang F, Zhang Z. Genome-wide long non-coding RNAs identified apanel of novel plasma biomarkers for gastric cancer diagnosis.Gastric Cancer. 2019 Jul;22(4):731-741.
ZhengR, Du M, Zhang B, XinJ, Chu H, Ni M, Zhang Z, Gu D, Wang M. Body mass index (BMI)trajectories and risk of colorectal cancer in the PLCO cohort. Br JCancer. 2018 Jul;119(1):130-132.
