Du Guizhen

发布者:公共卫生学院发布时间:2022-10-23浏览次数:503

Associate Professor of  Toxicology

Member of  Chinese Society of  Toxicology

Member of  Jiangsu Society of  Toxicology

guizhendu@njmu.edu.cn

杜桂珍, 博士 教授

Guizhen DU, PhD 


Research Interest

Reproductive and Developmental Toxicology


Education 

Nanjing Medical University, Preventive Medicine, B.S. (2003.09-2008.06)

Nanjing Medical University, Toxicology, Ph.D. (2008.09-2013.06)

University of  California, Los Angeles (UCLA), USA, Human Genetics, Visiting Project Scientist (2014.02-2016.01)


Honors and Awards: 

2021   Zhaoxibao Teachers Fellowship, Nanjing Medical University


Ongoing Research Projects

PI, The role of circKAT6B/miR-217/TCF12 axis in triclosan-induced trophoblast cell function abnormality and early spontaneous abortions, NSFC, 82173550 

 

Selected Papers

1. Dong G, Zhang R, Hu Q, Martin EM, Qin Y, Lu C, Xia Y, Wang X, Du G*. Prothioconazole induces cell cycle arrest by up-regulation of EIF4EBP1 in extravillous trophoblast cells. Arch Toxicol. 2022. 96(2):559-570.

2. Huang Z, Yu H, Du G (co-first author), Han L, Huang X, Wu D, Han X, Xia Y, Wang X, Lu C. Enhancer RNA lnc-CES1-1 inhibits decidual cell migration by interacting with RNA-binding protein FUS and activating PPARγ in URPL. Mol Ther Nucleic Acids. 2021. 24:104-112.

3. Du G, Yu M, Xu Q, Huang Z, Huang X, Han L, Fan Y, Zhang Y, Wang R, Xu S, Han X, Fu G, Lv S, Qin Y, Wang X, Lu C, Xia Y. Hypomethylation of PRDM1 is associated with recurrent pregnancy loss. J Cell Mol Med. 2020. 24(12): 7072-7077.

4. Du G*, Hu J, Huang Z, Yu M, Lu C, Wang X, Wu D. Neonatal and juvenile exposure to perfluorooctanoate (PFOA) and perfluorooctane sulfonate (PFOS): advance puberty onset and kisspeptin system disturbance in female rats. Ecotoxicology and Environmental Safety. 2019. 167:412-421.

5. Du G*, Yu M, Wang L, Hu W, Song L, Lu C, Wang X. Transcriptome and DNA Methylome Dynamics During Triclosan Induced Cardiomyocyte Differentiation Toxicity. Stem Cells International. 2018. 2018: 8608327.