Associate Professor of Toxicology
Member of Chinese Society of Toxicology
Member of Jiangsu Society of Toxicology
guizhendu@njmu.edu.cn
杜桂珍, 博士 副教授
Guizhen DU, PhD
Research Interest
Reproductive and Developmental Toxicology
Education
Nanjing Medical University, Preventive Medicine, B.S. (2003.09-2008.06)
Nanjing Medical University, Toxicology, Ph.D. (2008.09-2013.06)
University of California, Los Angeles (UCLA), USA, Human Genetics, Visiting Project Scientist (2014.02-2016.01)
Honors and Awards:
2021 Zhaoxibao Teachers Fellowship, Nanjing Medical University
Ongoing Research Projects
l PI, The role of circKAT6B/miR-217/TCF12 axis in triclosan-induced trophoblast cell function abnormality and early spontaneous abortions, NSFC, 82173550
Selected Papers
1. Dong G, Zhang R, Hu Q, Martin EM, Qin Y, Lu C, Xia Y, Wang X, Du G*. Prothioconazole induces cell cycle arrest by up-regulation of EIF4EBP1 in extravillous trophoblast cells. Arch Toxicol. 2022. 96(2):559-570.
2. Huang Z, Yu H, Du G (co-first author), Han L, Huang X, Wu D, Han X, Xia Y, Wang X, Lu C. Enhancer RNA lnc-CES1-1 inhibits decidual cell migration by interacting with RNA-binding protein FUS and activating PPARγ in URPL. Mol Ther Nucleic Acids. 2021. 24:104-112.
3. Du G, Yu M, Xu Q, Huang Z, Huang X, Han L, Fan Y, Zhang Y, Wang R, Xu S, Han X, Fu G, Lv S, Qin Y, Wang X, Lu C, Xia Y. Hypomethylation of PRDM1 is associated with recurrent pregnancy loss. J Cell Mol Med. 2020. 24(12): 7072-7077.
4. Du G*, Hu J, Huang Z, Yu M, Lu C, Wang X, Wu D. Neonatal and juvenile exposure to perfluorooctanoate (PFOA) and perfluorooctane sulfonate (PFOS): advance puberty onset and kisspeptin system disturbance in female rats. Ecotoxicology and Environmental Safety. 2019. 167:412-421.
5. Du G*, Yu M, Wang L, Hu W, Song L, Lu C, Wang X. Transcriptome and DNA Methylome Dynamics During Triclosan Induced Cardiomyocyte Differentiation Toxicity. Stem Cells International. 2018. 2018: 8608327.