D
irector,Department of Toxicology, School of Public Health, Nanjing MedicalUniversity.
Professor of Toxicology
Chairman,Asian Consortium for Arsenic and Health Research (ACAHR)
Deputy,Society of Chinese Toxicology Association (CTA)
Deputy,Chinese Environmental Mutagen Society(CEMS)
刘起展, 博士教授
Qizhan Liu,MD, PhD
Research Interest
Mechanism and Prevention of Environmental Factors-induced Damages
Biochemical and Molecular Toxicology.
Education
Hunan Medical College (HMC),Preventive Medicine, B. S. (1981.09~1986.06)
Sun Yat-sen University(SYSU), Labour Hygenesis, M. S. (1986.09~1989.06)
Sun Yat-sen University(SYSU), Toxicology, Ph. D.. (2000.09~2003.06)
Nanjing Medical University (NMU),Toxicology, Post-doctoralFellow. (2004.11~2007.05)
The University of Alabama atBirmingham (UAB), Birmingham,AL USA, Tumor Bioglogy,VisitingScientist. (2007.11~2009.05).
Honors and Awards:
2013 OutstandingProfessor of Nanjing Medical University (First Class)
2013 333project of Jiangsu province (Second Class)
Ongoing Research Projects
PI,A studyon the mechanismof autophagy and epithelium-fibroblast cross-talk mediated bycircRNA_0026344 and exosome in cigarette smoking- inducedchronic obstructive pulmonary diseases.NSFC, 81973085.
PI,A studyon mechanism and risk assessment of arsenic exposure-induced healthhazard based on hypoxia inducible factor pathway and exosomenon-coding RNA.NSFC,81730089.
PI,The roles andinterventions of inflammation to EMT mediated by STAT3-regulatedlncRNA HOTALR in cigarette smoking-induced chronic obstructivepulmonary disease (COPD) and lung cancer.NSFC, 81473011.
PI,Epigeneticmechanism and intervention of coal pollution endemic arsenicpoisoning. NSFC,81430077
Selected Papers
Cheng Cheng, Yan Wu, Tian Xiao,Junchao Xue, Jing Sun, Haibo Xia, Huimin Ma, Lu Lu, Junjie Li, AiminShi, Tao Bian, Qizhan Liu(刘起展)*.METTL3-mediated m6A modification of ZBTB4 mRNA is involved in thesmoking-induced EMT in cancer of the lung. Molecular Therapy-NucleicAcids. 2021; 23: 487-500.
Hao Wu, Huimin Ma, Lumin Wang,Huazhong Zhang, Lu Lu, Tian Xiao, Cheng Cheng, Peiwen Wang, Yi Yang,Meng Wu, Suhua Wang, Jinsong Zhang, Qizhan Liu(刘起展)*.Regulation of lung epithelial cell senescence in smokinginducedCOPD/emphysema by microR-125a-5p via Sp1 mediation of SIRT1/HIF-1a.International Journal of Biological Sciences. 2022; 18(2): 661–674.
Tian Xiao, Zhonglan Zou, JunchaoXue, Binafsha Manzoor Syed, Jing Sun, Xiangyu Dai, Ming Shi, JunjieLi, Shaofeng Wei, Huanwen Tang, Aihua Zhang, Qizhan Liu(刘起展)*.LncRNA H19-mediated M2 polarization of macrophages promotesmyofibroblast differentiation in pulmonary fibrosis induced byarsenic exposure. Environmental Pollution. 2021; 268: 115810.
Peiwen Wang, Tian Xiao, JunjieLi, Dapeng Wang, Jing Sun, Cheng Cheng, Huimin Ma, Junchao Xue, YanLi, Aihua Zhang, Qizhan Liu(刘起展)*.miR-21 in EVs from pulmonary epithelial cells promotes myofibroblastdifferentiation via glycolysis in arsenic-induced pulmonaryfibrosis. Environmental Pollution. 2021; 286: 117259.
Junjie Li, Junchao Xue, MinLing, Jing Sun, Tian Xiao, Xiangyu Dai, Qian Sun, Cheng Cheng, HaiboXia, Yongyue Wei, Feng Chen, Qizhan Liu(刘起展)*.MicroRNA-15b in extracellular vesicles from arsenite-treatedmacrophages promotes the progression of hepatocellular carcinomas byblocking the LATS1-mediated Hippo pathway. Cancer Letters. 2021;497: 137–153.
