D
epartment of Toxicology, School of PublicHealth, Nanjing Medical University
Associate Professor of Toxicology
ChengXu, PhD
Research Interest
Environment/EnvironmentalPollutants and Human Health
Education
Nanjing Medical University, Preventive Medicine, B.S. (2007.9-2012.7)
Nanjing Medical University, Toxicology, Ph.D. (2012.9-2017.6)
Nanjing Children's Hospital, Postdoctoral Fellow (2017.8-2020.6)
Nanjing Medical University, Postdoctoral Fellow (2020.7-2022.7)
Ongoing Research Projects
PI , Roles and mechanisms of C/EBPbeta-PKCepsilon-ERK1/2 signaling path way in congenital heart disease-associated pulmonaryhypertension.NSFC,81900281
PI,Theeffect and molecular mechanism of perfluorooctane sulfonates exposure on cardiac development.China Postdoctoral Science Foundation, 2018M630585
PI,Studyon the role and molecular mechanism of nickel and non syndromicpremature closure of sagittal suture.China Postdoctoral Science Foundation, 2021M691641
PI,Effectsand mechanisms of cadmium exposure on osteoblast differentiation andcraniosynostosis via Notch1/Hes-1/DEPTOR/autophagy pathway.China Postdoctoral Science Foundation, 2022T150331
Selected Papers
1.Xu C,Xu J, Zhang X, Xu S, Liu Q, Weng Z, Gu A. Serum nickel is associatedwith craniosynostosis risk: Evidence from humans and mice.Environment International 2021, 146: 106289.
2. XuC, Weng Z, Liang J,Liu Q, Zhang X, Xu J, Li Q, Zhou Y, Gu A. Shift Work, GeneticFactors, and the Risk of Heart Failure: A Prospective Study of the UKBiobank. Mayo Clin Proc. 2022 Jun;97(6):1134-1144.
3.Xu C,Liang J, Xu S, Liu Q, Xu J, Gu A. Increased serum levels of aldehydesare associated with cardiovascular disease and cardiovascular riskfactors in adults. Journal of Hazardous Materials 2020, 400: 123134.
4.Huang H, Wang Q, He X, Wu Y, XuC#.Association between polyfluoroalkyl chemical concentrations andleucocyte telomere length in US adults. The Science of the TotalEnvironment 2019, 653: 547-553.
5.Weng Z, Liu Q, Yan Q, Liang J, Zhang X, Xu J, Li W, XuC#,Gu A. Associations of genetic risk factors and air pollution withincident hypertension among participants in the UK Biobank study.Chemosphere. 2022 Mar 23;299:134398.
