Han Xiumei

发布者：公共卫生学院发布时间：2022-10-23浏览次数：453

韩秀梅Xiumei HAN

hanxiumei@njmu.edu.cn


ResearchInterest

Environmental Pollution/Birthcohort

EDCs/Spontaneous abortion

Stemcell/Developmental Toxicology


Education

Baotou   Medical  College,  Preventive  Medicine, B.S. (2004.9-2009.7)

Nanjing  Medical  University,  Hygiene  Toxicology, M.S. (2009.9-2012.7)


ResearchProject

  1. PI. Effects of pregnancy exposure to pentachlorophenol on early  spontaneous abortion and autophagy mechanism. NSFC,81502832.

  2. PI. Study on the role and molecular mechanism of  Mir-141 in male  spermatogenesis abnormalities caused by representativephytoestrogens.General Education Program of Nanjing MedicalUniversity. 2013NJMU022.


SelectedPapers

  1. HanX#,Lu T, Hu Y, Duan J, Guan Y, Huang X, Zhou J, Huang R, Tang M, Sun R,Wang Y, Song L, Xia Y, Wang X, Chen M, Chen T. A metabolomic studyon the effect of prenatal exposure to Benzophenone-3 on spontaneousfetal loss in mice. Ecotoxicol Environ Saf. 2022 Mar 15;233:113347.doi: 10.1016/j.ecoenv.2022.113347. Epub 2022 Feb 24. PMID: 35219956.

  2. XuQ, Yu M, Zhou Y, Huang Z, Huang X, Xu B, Zhou K, Chen X, Xia Y, WangX, Lu C,HanX#.Effects of 2,2',4,4'-tetrabromodiphenyl ether on the development ofmouse embryonic stem cells. Reprod Toxicol. 2021 Sep 20;106:18-24.doi: 10.1016/j.reprotox.2021.09.008. Epub ahead of print. PMID:34547414.

  3. HanX#,Wang Y, Chen T, Wilson MJ, Pan F, Wu X, Rui C, Chen D, Tang Q, Wu W.Inhibitionof progesterone biosynthesis induced by deca-brominated diphenylether (BDE-209) in mouse Leydig tumor cell (MLTC-1).ToxicolIn Vitro. 2019 Oct;60:383-388. doi: 10.1016/j.tiv.2019.05.016. Epub2019 May 24.PMID: 31132478

  4. HuangX, HanX#（co-firstauthor）,Huang Z, Yu M, Zhang Y, Fan Y, Xu B, Zhou K, Song L, Wang X, Lu C,Xia Y*. Maternal pentachlorophenol exposure induces developmentaltoxicity mediated by autophagy on pregnancy mice. Ecotoxicol EnvironSaf. 2019, 169:829-836.

  5. HanX#,Tang R#, Chen X, Xu B, Qin Y, Wu W, Hu Y, Xu B, Song L, Xia Y*, WangX*. 2,2',4,4'-Tetrabromodiphenyl ether (BDE-47) decreasesprogesterone synthesis through cAMP-PKA pathway and P450scc downregulation in mouse Leydig tumor cells. Toxicology. 2012,302(1):44-50.