ErbaoZhang, PhD, Associate Professor
Department of Epidemiology,School of Public Health, Nanjing Medical University
JiangsuKey Lab of Cancer Biomarkers, Prevention and Treatment, Collaborative Innovation Center for Cancer Personalized Medicine, Nanjing Medical University
E-mail:erbaozhang@njmu.edu.cn
ResearchInterest
Basicresearch on tumorigenesis
Education
Nanjing Medical University, Biotechnology, B.S. (2006.9-2010.7)
Nanjing Medical University, Biochemistry and Molecular Biology, M.S.(2010.9-2013.7)
Nanjing Medical University, Biochemistry and Molecular Biology, Ph.D.(2013.9-2016.7)
Nanjing Medical University, Epidemiology, postdoc (2016-2018)
HonorSand Awards:
2021 First Prize of Science and Technology Award of China Anti-Cancer Association
2019 National College Student"Challenge Cup" Competition Jiangsu Province Special Prize , Instructor.
OngoingResearch Projects
PI, Long noncoding RNA FAM86J Pregulates mitochondrial metabolism and promotes the tumorigenesis ofnon-small cell lung cancer via mediating phase separation, NSFC,82172992.
PI, Copy numberamplification-activated long noncoding RNA FAM86JP acts as a"molecule scaffolding" to regulate mitochondrialmetabolism to promote tumorigenesis of lung cancer, Natural ScienceFoundation of Jiangsu Province, BK20211253.
SelectedPapers
(1)EB Zhang#*,XZ He#, CG Zhang#, J Su#, XY Lu, XX Si, JF Chen, DD Yin*, L Han*, WDe*. A novel long noncoding RNA HOXC-AS3 mediates tumorigenesis ofgastric cancer by binding to YBX1. GenomeBiology, 2018 Oct4;19(1):154. (First Author and Co-Corresponding Author)
(2)EB Zhang#,L Han#, DD Yin#, XZ He, LZ Hong, XX Si, MT Qiu, TP Xu, W De*, L Xu*,YQ Shu*, JF Chen*. H3K27 acetylation activated-long non-coding RNACCAT1 affects cell proliferation and migration by regulating SPRY4and HOXB13 expression in esophageal squamous cell carcinoma.Nucleic Acids Research,2017 Apr 7;45(6):3086-3101. (First Author)
(3)XY Lu#, J Wang #, W Wang #, CF Lu #, TY Qu, XZ He, XY Liu, RH Guo*,EB Zhang*.Copy number amplification and SP1-activated lncRNA MELTF-AS1regulates tumorigenesis by driving phase separation of YBX1 toactivate ANXA8 in non-small cell lung cancer. Oncogene,2022 Jun;41(23):3222-3238. (Co-Corresponding Author)
(4)C Zhang#, Qi Sun#, X Zhang#, N Qin, ZN Pu, YY Gu, CW Yan, M Zhu, JCDai, C Wang, N Li, GF Jin, HX Ma, ZB Hu,EB Zhang*, FW Tan*, HBShen*.Gene amplification-driven RNA methyltransferase KIAA1429promotes tumorigenesis by regulating BTG2 via m6A-YTHDF2-dependent inlung adenocarcinoma. CancerCommunications, 2022Jul;42(7):609-626. (Co-Corresponding Author)
(5)DD Yin#, XY Lu#, J Su#, XZ He, W De, JS Yang*, W Li*, L Han*, EBZhang*. Long noncodingRNA AFAP1-AS1 predicts a poor prognosis and regulates non-small celllung cancer cell proliferation by epigenetically repressing p21expression. MolecularCancer, 2018 May24;17(1):92. (Co-Corresponding Author)
(6)TW Xu#, S Yan#, LH Jiang#, SX Yu#, TY Lei, DL Yang, BB Lu, CC Wei, EBZhang*, ZX Wang*. GeneAmplification-Driven Long Noncoding RNA SNHG17 Regulates CellProliferation and Migration in Human Non-Small-Cell Lung Cancer.Molecular Therapy-Nucleic Acids,2019 Sep 6;17:405-413. (Co-Corresponding Author)
(7)XW Wang#, SH Ju#, Y Chen#, QF Qian#, CW Yan, SZ Chen, YT Chang, YDXu, ZJ Ma, C Zhang, N Qin, YY Gu, C Wang*,EB Zhang*, ZB Hu*.Hypomethylation-activated cancer-testis gene SPANXC promotes cellmetastasis in lung adenocarcinoma. Journalof Cellular and Molecular Medicine,2019 Nov;23(11):7261-7267. (Co-Corresponding Author)
(8) XZ He#, J Wang#, J Chen#, LHan#, XY Lu, DS Miao*, DD Yin*, QH Geng*,EB Zhang*. lncRNA UCA1Predicts a Poor Prognosis and Regulates Cell Proliferation andMigration by Repressing p21 and SPRY1 Expression in GC. MolecularTherapy-Nucleic Acids,2019 Dec 6;18:605-616. (Co-Corresponding Author)
(9)EB Zhang#,DD Yin#, M Sun, R Kong, XH Liu, LH You, L Han, R Xia, KM Wang, JSYang, W De*, YQ Shu*, ZX Wang*. P53-regulated long non-coding RNATUG1 affects cell proliferation in human non-small cell lung cancer,partly through epigenetically regulating HOXB7 expression. CellDeath & Disease,(2014) 5, e1243. (First Author)
(10)C Wang#, YY Gu#, EBZhang#, K Zhang, NQin, JC Dai, M Zhu, J Liu, KP Xie, Y Jiang, XJ Guo, MX Liu, GF Jin,HX Ma, T Jiang, R Yin, YK Xia, L Liu, SY Wang, B Shen, R Huo, L Xu,JH Sha, B Qu, HB Shen*, ZB Hu*. A cancer-testis non-coding RNALIN28B-AS1 activates driver gene LIN28B by interacting with IGF2BP1in lung adenocarcinoma. Oncogene,2019 Mar;38(10):1611-1624. (Co-First Author)
