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您现在的位置: 南京医科大学公共卫生学院 >> 院系介绍 

魏永越

魏永越,博士

生物统计学   副教授

ywei@njmu.edu.cn

 

魏永越,南京医科大学临床医学本科(2001-2006),生物统计学博士(2006-2011),导师:陈峰教授。哈佛大学公共卫生学院环境及肿瘤基因组学博士后(2012-2015,导师:David C. Christiani。中华预防医学会生物统计分会青年委员(2015-)。获得国家自然科学基金青年基金一项(2015),江苏省自然科学基金青年基金一项(2014),美国Harvard-NIEHS pilot study一项(2013),及南京医科大学优秀中青年教师支持计划(2015)。参与多项十二五重大专项、国家自然基金重点项目及面上项目的统计设计及分析。聚焦于组学数据的因果推断及疾病发生风险/预后研究,并发表英文文章五十余篇,其中第一/通讯作者9篇,包括国际著名期刊AJRCCMIF 13.1)、Cancer ResearchIF 8.556)、CHESTIF 7.1)、EBioMedicineJournal Expo Science Environ Epi等。国家注册软件设计师(2005),编制的临床试验在线动态随机分组系统并申请软件著作权一项(2009SR042180),已服务多项II/III期临床试验。目前的研究方向为基于多种组学数据的因果推断及疾病预后模型研究。

 

教育经历:

2006/09–2011/06,南京医科大学,公共卫生学院,流行病与卫生统计学系,博士

导师:陈峰教授

2001/09–2006/06,南京医科大学,临床医学(心理卫生方向),学士

  

工作经历:

2011/09-至今,南京医科大学公共卫生学院,流行病与卫生统计学系,讲师

2012/06-2015/08,美国哈佛大学公共卫生学院,环境卫生学系,博士后,肿瘤及环境基因组学方向,导师:David C. Christiani

 

获得荣誉:

1.      2015年,中华预防医学会生物统计分会青年委员

2.      2015Harvard Chinese Life Science Research Award. Chinese Scholars And Scientists Association at Harvard Medical School

3.      2015年,全国大学生统计建模大赛大数据统计建模类——本科生组二等奖指导老师(证书编号:2015IAB014-1

4.      2015年,“汇丰杯”中国高校SAS数据分析大赛团体五十强指导老师

5.      2015年,南京医科大学“优秀中青年教师支持计划”

6.      2016年,“汇丰杯”中国高校SAS数据分析大赛三十强指导老师

7.      2016年,“汇丰杯”中国高校SAS数据分析大赛优秀组织奖

 

主持科研项目:

1.    国家自然科学基金青年基金:基于生物学调控网络的肺癌多平台组学数据的整合分析方法研究(NSFC 81402764),201501—201712月,23万,在研,主持。

2.    江苏省自然科学基金青年基金:基于基因调控网络的肺癌多平台组学研究整合分析方法学(BK20140907),201407—20176月,20万,在研,主持。

3.    江苏省优势学科二期建设项目青年创新骨干人才培育项目(2015.09-2016.09),在研,5万。

4.    美国国家环境健康科学研究所前期课题(NIEHS pilot project): Metal Exposure, Metabolomics, and Birth Outcome, 10/01/2013–03/01/2015$2万,已结题,主持。

5.    国家自然科学基金重点项目(NSFC81530088):基于人群的生物医学多层面数据整合方法及肿瘤风险预测研究,274万,在研,参与。

6.    国家重点研发计划——战略性国际科技合作重点专项(2016YFE0204900):基于出生队列的重金属暴露与不良出生结局的国际合作研究,721万,在研,研究骨干。

 

专利/软件著作权:

1.      南京医科大学临床研究受试者在线随机分组软件软件. 登记号:2009SR042180

 

教授课程:

1.      SAS高级编程

2.      多元统计分析及SAS基础

3.      研究设计

4.      医学统计学(医学本科专业、研究生,等)

 

社会任职

2015, International Journal of Cancer, reviewer

2016, Environmental Research, reviewer

2016, Journal of Biomedical Research, Arts Editor

 

发表论文(#第一作者,*通讯作者)

1.       Shen S(#), Wang G, Shi Q, Zhang R, Zhao Y, Wei Y(*), Chen F(*), Christiani DC. Seven-CpG-based prognostic signature coupled with gene expression predicts survival of oral squamous cell carcinoma. Clin Epigenetics. 2017 Aug 24;9:88. (IF, 4.99)

2.       Wei Y(#), Tejera P, Wang Z, Zhang R, Chen F, Su L, Lin X, Bajwa EK, Thompson TB, Christiani DC*. A missense genetic variant in LRRC16A/CARMIL1 improves ARDS survival by attenuating platelet count decline. AJRCCM. 2016 epub. DOI: 10.1164/rccm.201605-0946OC. (with AJRCCM editorial and Lancet Resp Med commentary, IF, 13.204)

3.       Zhang Y(#), Wei Y(#), Jiang B, Chen L, Bai H, Zhu X, Li X, Zhang H, Yang Q, Ma J, Xu Y, Ben J, Christiani DC, Chen Q. Scavenger Receptor A1 Prevents Non-Small Cell Lung Cancer Metastasis by Suppressing Macrophage Serum Amyloid A1 Production. Cancer Res. 2017 Apr 1;77(7):1586-1598. (IF, 9.122)

4.       Wei Y(#), Wang Z, Su L, Chen F, Tejera P, Bajwa EK, Wurfel MM, Lin X, Christiani DC(*). Platelet Count Mediates the Contribution of a Genetic Variant in LRRC16A to ARDS Risk. Chest. 2014 epub. 2015 Mar;147(3):607-17. doi: 10.1378/chest.14-1246. (with editorial) (IF, 7.483)

5.       Wei Y(#), Shi Q(#), Wang Z, Zhang R, Su L, Quamruzzaman Q, Rahman M, Chen F*, Christiani DC*. Maternal/fetal metabolomes appear to mediate the impact of arsenic exposure on birth weight: a pilot study. Maternal/fetal metabolomes appear to mediate the impact of arsenic exposure on birth weight: a pilot study. Journal Expo Science Environ Epi. 2016. Epub 10.1038/jes.2016.74. (IF, 2.927)

6.       Huang L(#), Wei Y(#), Shen S, Shi Q, Bai J, Li J, Qin S*, Yu H*, Chen F. Therapeutic effect of apatinib on overall survival is mediated by prolonged progression-free survival in advanced gastric cancer patients. Oncotarget. 2016 Oct 25. doi: 10.18632/oncotarget.12897. (IF, 5.008)

7.       Xia ZG, Yin HF, Long Y, Cheng L, Yu LJ, Guo WJ, Zhu XD, Li J, Wang YN, Yang YJ, Wang JC, Jin L, Qiu LX(*), Wei Y(*). Genetic variant of miR-146a rs2910164 C>G and gastric cancer susceptibility. Oncotarget. 2016 Apr 18. doi: 10.18632/oncotarget.8814. (IF, 5.008)

8.       Huang R(#), Wei Y(#), Hung RJ, Liu G, Su L, Zhang R, Zong X, Zhang ZF, Morgenstern H, Bruske I, Heinrich J, Hong YC, Kim JH, Cote M, Wenzlaff A, Schwartz AG, Stucker I, McLaughlin J, Marcus MW, Davies MP, Liloglou T, Field JK, Matsuo K, Barnett M, Thornquist M, Goodman G, Wang Y, Chen S, Yang P, Duell EJ, Andrew AS, Lazarus P, Muscat J, Woll P, Horsman J, Dawn Teare M, Flugelman A, Rennert G, Zhang Y, Brenner H, Stegmaier C, van der Heijden EH, Aben K, Kiemeney L, Barros-Dios J, Perez-Rios M, Ruano-Ravina A, Caporaso NE, Bertazzi PA, Landi MT, Dai J, Shen H, Fernandez-Tardon G, Rodriguez-Suarez M, Tardon A, Christiani DC(*). Associated Links Among Smoking, Chronic Obstructive Pulmonary Disease, and Small Cell Lung Cancer: A Pooled Analysis in the International Lung Cancer Consortium. EBioMedicine. 2015;2(11):1677-1685. (with commentary)

9.       Wei Y(#), Wang Z(#), Chang C, Fan T, Su L, Chen F, Christiani DC(*). Global metabolomic profiling reveals an association of metal fume exposure and plasma unsaturated fatty acids. PLoS ONE. 2013; 15; 8(10): e77413. (IF, 3.534)

 

联合发表的部分论文:

10.   Duan W, Zhao Y, Wei Y, Yang S, Bai J, Shen S, Du M, Huang L, Hu Z, Chen F. A fast algorithm for Bayesian multi-locus model in genome-wide association studies. Mol Genet Genomics. 2017 Aug;292(4):923-934.

11.   Liu W, Wang L, Wei Y, Li X, Gao C, Zhou J, Wang L, Sun Z, Chu H, Bai Y, Yang J. Interaction of Soluble CXC Ligand 16 and Cardiac Injury Markers in Hemodialysis Patients. Am J Nephrol. 2017;46(1):64-70.

12.   Wang Z, Claus Henn B, Wang C, Wei Y, Su L, Sun R, Chen H, Wagner PJ, Lu Q, Lin X, Wright R, Bellinger D, Kile M, Mazumdar M, Tellez-Rojo MM, Schnaas L, Christiani DC. Genome-wide gene by lead exposure interaction analysis identifies UNC5D as a candidate gene for neurodevelopment. Environ Health. 2017 Jul 28;16(1):81.

13.   Zhu Z, Liang L, Zhang R, Wei Y, Su L, Tejera P, Guo Y, Wang Z, Lu Q, Baccarelli AA, Zhu X, Bajwa EK, Taylor Thompson B, Shi GP, Christiani DC. Whole blood microRNA markers are associated with acute respiratory distress syndrome. Intensive Care Med Exp. 2017 Aug 30;5(1):38.

14.   Zhaozhong ZhuLiming LiangRuyang ZhangYongyue WeiLi SuPaula TejeraZhaoxi WangQuan LuAndrea BaccarelliXi ZhuEdnan BajwaB. T. ThompsonDavid C. Christiani. Whole Blood miR-181a, miR-92a, and miR-424 Are Risk Factors of Acute Respiratory Distress Syndrome. American Journal of Respiratory and Critical Care Medicine 2017;195:A5223

15.   Yongchu Pan, Hongliang Liu, YanruWang, Xiaozheng Kang, Zhensheng Liu, KourosOwzar, Younghun Han, Li Su, Yongyue Wei, Rayjean J. Hung, Yonathan Brhane, John McLaughlin, Paul Brennan, Heike Bickeböller, Albert Rosenberger, Richard S. Houlston, Neil Caporaso, Maria Teresa Landi, Joachim Heinrich, Angela Risch, Xifeng Wu, Yuanqing Ye, DavidC. Christiani, Christopher I. Amos & Qingyi Wei. Associations between genetic variants in mRNA splicing-related genes and risk of lung cancer: a pathway-based analysis from published GWASs. Sci Rep. 2017 Mar 17;7:44634. doi: 10.1038/srep44634.

16.   Rosenberger ASohns MFriedrichs SHung RJFehringer GMcLaughlin JAmos CIBrennan PRisch ABrüske ICaporaso NELandi MTChristiani DCWei YBickeböller H. Gene-set meta-analysis of lung cancer identifies pathway related to systemic lupus erythematosus. PLoS One. 2017 Mar 8;12(3):e0173339. doi: 10.1371/journal.pone.0173339. eCollection 2017.

17.   Yin JLiu HLiu ZOwzar KHan YSu L, Wei YHung RJBrhane YMcLaughlin JBrennan PBickeboeller HRosenberger AHoulston RSCaporaso NLandi MTHeinrich JRisch AChristiani DCAmos CIWei Q. Pathway-analysis of published genome-wide association studies of lung cancer: A potential role for the CYP4F3 locus. Mol Carcinog. 2017 Feb 2. doi: 10.1002/mc.22622. [Epub ahead of print]

18.   Zhaoxi WangYongyue WeiPaula TejeraLi Su Ednan K. BajwaDavid C. Christiani. A Functional Missense SNP in LRRC16A Contributes to an Improved Prognosis of ARDS Patients Mediated Through Attenuated Platelet Count Decline in ICU. AJRCCM 2016;193:A7489

19.   Zhaoxi WangYongyue WeiRuyang ZhangLi SuRadhika KhetaniShannan Ho SuiXihong LinEdnan K. BajwaB. T. ThompsonMark M. WurfelDavid C. Christiani. Targeted Sequencing of Top Loci Identified by Genome-Wide Association Study (GWAS) Associated with Acute Respiratory Distress Syndrome (ARDS). AJRCCM 2016;193:A7792.

20.   Zhaozhong ZhuYongyue WeiLi SuRuyang ZhangPaula TejeraZhaoxi WangQuan LuLiming LiangAndrea BaccarelliDavid C. Christiani. Whole Blood MicroRNA Biomarkers in Acute Respiratory Distress Syndrome. AJRCCM 2016;193:A2915. Conference Abstract.

21.   Ruyang ZhangZhaoxi WangYongyue Wei,  Zhaozhong ZhuLi SuEdnan K. BajwaB. T. Thompson,David C. Christiani. A Two-Stage Association Study Identifies a High Risk Window of Acute Respiratory Distress Syndrome Onset Time Correlated with Poor 28 Day Overall Survival. AJRCCM 2016;193:A7794. Conference Abstract.

22.   Paula Tejera, Ruyang ZhangYongyue WeiZhaozhong ZhuZhaoxi WangLi SuDavid C. Christiani. Genome-Wide Expression Profiling of Acute Respiratory Distress Syndrome (ARDS). AJRCCM 2016;193:A2664. Conference Abstract.

23.   Zhang R, Wang Z, Tejera P, Frank AJ, Wei Y, Su L, Zhu Z, Guo Y, Chen F, Bajwa EK, Thompson BT, Christiani DC. Late-onset moderate to severe acute respiratory distress syndrome is associated with shorter survival and higher mortality: a two-stage association study. Intensive Care Med. 2016 Dec 28.

24.   Yuan H, Liu H, Liu Z, Owzar K, Han Y, Su L, Wei Y, Hung RJ, McLaughlin J, Brhane Y, Brennan P, Bickeboeller H, Rosenberger A, Houlston RS, Caporaso N, Landi MT, Heinrich J, Risch A, Christiani DC, Gümüş ZH, Klein RJ, Amos CI, Wei Q. A Novel Genetic Variant in Long Non-coding RNA Gene NEXN-AS1 is Associated with Risk of Lung Cancer. Sci Rep. 2016 Oct 7;6:34234.

25.   Zuber V, Marconett CN, Shi J, Hua X, Wheeler W, Yang C, Song L, Dale AM, Laplana M, Risch A, Witoelar A, Thompson WK, Schork AJ, Bettella F, Wang Y, Djurovic S, Zhou B, Borok Z, van der Heijden HF, de Graaf J, Swinkels D, Aben KK, McKay J, Hung RJ, Bikeböller H, Stevens VL, Albanes D, Caporaso NE, Han Y, Wei Y, Panadero MA, Mayordomo JI, Christiani DC, Kiemeney L, Andreassen OA, Houlston R, Amos CI, Chatterjee N, Laird-Offringa IA, Mills IG, Landi MT. Pleiotropic Analysis of Lung Cancer and Blood Triglycerides. J Natl Cancer Inst. 2016 Aug 26;108(12). pii: djw167. doi: 10.1093/jnci/djw167. Print 2016 Dec.

26.   Wagner PJ, Park HR, Wang Z, Kirchner R, Wei Y, Su L, Stanfield K, Guilarte TR, Wright RO, Christiani DC, Lu Q. In Vitro Effects of Lead on Gene Expression in Neural Stem Cells and Associations between Upregulated Genes and Cognitive Scores in Children. Environ Health Perspect. 2016 Aug 26. [Epub ahead of print]

27.   Wang Z, Chen X, Liu K, Xie W, Wang H, Wei Y, Tang L, Zhu Y. Small pulmonary vascular alteration and acute exacerbations of COPD: quantitative computed tomography analysis. Int J Chron Obstruct Pulmon Dis. 2016 Aug 22;11:1965-71.

28.   Carreras-Torres R, Haycock PC, Relton CL, Martin RM, Smith GD, Kraft P, Gao C, Tworoger S, Le Marchand L, Wilkens LR, Park SL, Haiman C, Field JK, Davies M, Marcus M, Liu G, Caporaso NE, Christiani DC, Wei Y, Chen C, Doherty JA, Severi G, Goodman GE, Hung RJ, Amos CI, McKay J, Johansson M, Brennan P. The causal relevance of body mass index in different histological types of lung cancer: A Mendelian randomization study. Sci Rep. 2016 Aug 4;6:31121. doi: 10.1038/srep31121.

29.   Patel YM, Park SL, Han Y, Wilkens LR, Bickeböller H, Rosenberger A, Caporaso N, Landi MT, Bruske I, Risch A, Wei Y, Christiani DC, Brennan P, Houlston RS, McKay J, McLaughlin J, Hung RJ, Murphy SE, Stram DO, Amos CI, Le Marchand L. Novel Association of Genetic Markers Affecting CYP2A6 activity and Lung Cancer Risk. Cancer Res. 2016 Aug 3. pii: canres.0446.2016. [Epub ahead of print]

30.   Zanetti KA, Wang Z, Aldrich M, Amos CI, Blot WJ, Bowman ED, Burdette L, Cai Q, Caporaso N, Chung CC, Gillanders EM, Haiman CA, Hansen HM, Henderson BE, Kolonel LN, Marchand LL, Li S, McNeill LH, Ryan BM, Schwartz AG, Sison JD, Spitz MR, Tucker M, Wenzlaff AS, Wiencke JK, Wilkens L, Wrensch MR, Wu X, Zheng W, Zhou W, Christiani D, Palmer JR, Penning TM, Rieber AG, Rosenberg L, Ruiz-Narvaez EA, Su L, Vachani A, Wei Y, Whitehead AS, Chanock SJ, Harris CC. Genome-wide association study confirms lung cancer susceptibility loci on chromosomes 5p15 and 15q25 in an African-American population. Lung Cancer. 2016 Aug;98:33-42.

31.   Zhang Q, Zhao Y, Zhang R, Wei Y, Yi H, Shao F, Chen F. A Comparative Study of Five Association Tests Based on CpG Set for Epigenome-Wide Association Studies. PLoS One. 2016 Jun 3;11(6):e0156895.

32.   Fehringer G, Kraft P, Pharoah PD, Eeles RA, Chatterjee N, Schumacher FR, Schildkraut JM, Lindstrom S, Brennan P, Bickeböller H, Houlston RS, Landi MT, Caporaso NE, Risch A, Amin Al Olama A, Berndt SI, Giovannucci EL, Gronberg H, Kote-Jarai Z, Ma J, Muir K, Stampfer MJ, Stevens VL, Wiklund F, Willett WC, Goode EL, Permuth JB, Risch HA, Reid BM, Bezieau S, Brenner H, Chan AT, Chang-Claude J, Hudson TJ, Kocarnik J, Newcomb PA, Schoen RE, Slattery ML, White E, Adank MA, Ahsan H, Aittomaki K, Baglietto L, Blomquist C, Canzian F, Czene K, Dos Santos Silva I, Eliassen AH, Figueroa JD, Flesch-Janys D, Fletcher O, Garcia-Closas M, Gaudet MM, Johnson N, Hall P, Hazra A, Hein R, Hofman A, Hopper JL, Irwanto A, Johansson M, Kaaks R, Kibriya MG, Lichtner P, Liu JJ, Lund E, Makalic E, Meindl A, Müller-Myhsok B, Muranen TA, Nevanlinna H, Peeters PH, Peto J, Prentice RL, Rahman N, Sanchez MJ, Schmidt DF, Schmutzler RK, Southey MC, Tamimi RM, Travis RC, Turnbull C, Uitterlinden AG, Wang Z, Whittemore AS, Yang XR, Zheng W, Buchanan DD, Casey G, Conti DV, Edlund CK, Gallinger S, Haile RW, Jenkins MA, Le Marchand L, Li L, Lindor NM, Schmit SL, Thibodeau SN, Woods MO, Rafnar T, Gudmundsson J, Stacey SN, Stefansson K, Sulem P, Chen YA, Tyrer JP, Christiani DC, Wei Y, Shen H, Hu Z, Shu XO, Shiraishi K, Takahashi A, Bossé Y, Obeidat M, Nickle D, Timens W, Freedman ML, Li Q, Seminara D, Chanock SJ, Gong J, Peters U, Gruber SB, Amos CI, Sellers TA, Easton DF, Hunter DJ, Haiman CA, Henderson BE, Hung RJ. Cross-cancer genome-wide analysis of lung, ovary, breast, prostate and colorectal cancer reveals novel pleiotropic associations. Cancer Res. 2016 Apr 20. pii: canres.2980.2015.

33.   Kang X, Liu H, Onaitis MW, Liu Z, Owzar K, Han Y, Su L, Wei Y, Hung RJ, Brhane Y, McLaughlin J, Brennan P, Bickeböller H, Rosenberger A, Houlston RS, Caporaso N, Landi MT, Heinrich J, Risch A, Wu X, Ye Y, Christiani DC, Amos CI, Wei Q; Transdisciplinary Research in Cancer of the Lung (TRICL) Research Team. Polymorphisms of the centrosomal gene (FGFR1OP) and lung cancer risk: a meta-analysis of 14 463 cases and 44 188 controls. Carcinogenesis. 2016 Mar;37(3):280-9.

34.   Ghosh CC, David S, Zhang R, Berghelli A, Milam K, Higgins SJ, Hunter J, Mukherjee A, Wei Y, Tran M, Suber F, Kobzik L, Kain KC, Lu S, Santel A, Yano K, Guha P, Dumont DJ, Christiani DC, Parikh SM. Gene control of tyrosine kinase TIE2 and vascular manifestations of infections. Proc Natl Acad Sci U S A. 2016 Mar 1;113(9):2472-7.

35.   Lu J, Gu H, Tang Q, Wu W, Yuan B, Guo D, Wei Y, Sun H, Xia Y, Ding H, Hu L, Chen D, Sha J, Wang X. Common SNP in hsa-miR-196a-2 increases hsa-miR-196a-5p expression and predisposes to idiopathic male infertility in Chinese Han population. Sci Rep. 2016 Jan 25;6:19825.

36.   Wang Y, Liu H, Ready NE, Su L, Wei Y, Christiani DC, Wei Q. Genetic variants in ABCG1 are associated with survival of non-small cell lung cancer patients. International journal of cancer. INT J CANCER. 2016.

37.   Kachuri L, Amos CI, McKay JD, Johansson M, Vineis P, Bueno-de-Mesquita HB, Boutron-Ruault MC, Johansson M, Quiros JR, Sieri S, Travis RC, Weiderpass E, Le Marchand L, Henderson BE, Wilkens L, Goodman GE, Chen C, Doherty JA, Christiani DC, Wei Y, Su L, Tworoger S, Zhang X, Kraft P, Zaridze D, Field JK, Marcus MW, Davies MP, Hyde R, Caporaso NE, Landi MT, Severi G, Giles GG, Liu G, McLaughlin JR, Li Y, Xiao X, Fehringer G, Zong X, Denroche RE, Zuzarte PC, McPherson JD, Brennan P, Hung RJ. Fine mapping of chromosome 5p15.33 based on a targeted deep sequencing and high density genotyping identifies novel lung cancer susceptibility loci. Carcinogenesis. 2016;37(1):96-105.

38.   Zhaoxi WangYongyue WeiLi SuXihong LinIan BarnettMark M. WurfelDavid C. Christiani. Genome-Wide Association Study and Global Expression Profiling Identified the BAD Gene as Associated with Acute Respiratory Distress Syndrome (ARDS). AJRCCM 2015;191:A4354.

39.   Zhu Y, Xu H, Zhu X, Wei Y, Yang G, Tang L, Xu Y. Which can predict left ventricular size and systolic function: cardiothoracic ratio or transverse cardiac diameter. Journal of X-ray science and technology. 2015;23(5):557-565.

40.   Zhang Z, Xu G, Wei Y, Zhu W, Liu X. Nut consumption and risk of stroke. European journal of epidemiology. 2015;30(3):189-196.

41.   Zhang Z, Xu G, Wei Y, Zhu W, Fan X, Liu X. Impact of chromosome 12p13 variants on ischemic stroke risk. The International journal of neuroscience. 2015:1-7.

42.   Kinsey CM, San José Estépar R, Wei Y, Washko GR, Christiani DC. Regional Emphysema of a Non-Small Cell Tumor Is Associated with Larger Tumors and Decreased Survival. Ann Am Thorac Soc. 2015 Jun 3.

43.   Wang Y, Wei Y, Gaborieau V, Shi J, Han Y, Timofeeva MN, Su L, Li Y, Eisen T, Amos CI, Landi MT, Christiani DC, McKay JD, Houlston RS. Deciphering associations for lung cancer risk through imputation and analysis of 12 316 cases and 16 831 controls. Eur J Hum Genet. 2015 Mar 25. doi: 10.1038/ejhg.2015.48. [Epub ahead of print]

44.   Brenner DR, Amos CI, Brhane Y, Timofeeva MN, Caporaso N, Wang Y, Christiani DC, Bickeboller H, Yang P, Albanes D, Stevens VL, Gapstur S, McKay J, Boffetta P, Zaridze D, Szeszenia-Dabrowska N, Lissowska J, Rudnai P, Fabianova E, Mates D, Bencko V, Foretova L, Janout V, Krokan HE, Skorpen F, Gabrielsen ME, Vatten L, Njolstad I, Chen C, Goodman G, Lathrop M, Vooder T, Valk K, Nelis M, Metspalu A, Broderick P, Eisen T, Wu X, Zhang D, Chen W, Spitz MR, Wei Y, Su L, Xie D, She J, Matsuo K, Matsuda F, Ito H, Risch A, Heinrich J, Rosenberger A, Muley T, Dienemann H, Field JK, Raji O, Chen Y, Gosney J, Liloglou T, Davies MP, Marcus M, McLaughlin J, Orlow I, Han Y, Li Y, Zong X, Johansson M, Liu G, Tworoger SS, Le Marchand L, Henderson BE, Wilkens LR, Dai J, Shen H, Houlston RS, Landi MT, Brennan P, Hung RJ. Identification of lung cancer histology-specific variants applying Bayesian framework variant prioritization approaches within the TRICL and ILCCO consortia. Carcinogenesis. 2015;36(11):1314-1326.

45.   Ahasic AM, Tejera P, Wei Y, Su L, Mantzoros CS, Bajwa EK, Thompson BT, Christiani DC. Predictors of Circulating Insulin-Like Growth Factor-1 and Insulin-Like Growth Factor-Binding Protein-3 in Critical Illness. Critical care medicine. 2015;43(12):2651-2659.

46.   Amy M. AhasicPaula TejeraYongyue WeiLi SuChristos MantzorosB. T. ThompsonDavid C. Christiani. Polymorphisms In The Insulin Growth Factor Pathway, And Circulating Insulin-Like Growth Factor-1 And Insulin-Like Growth Factor Binding Protein-3 In Medical Critical Illness. AJRCCM 2014;189:A1640.

47.   Zheng D, Chen Y, Gao C, Wei Y, Cao G, Lu N, Hou Y, Jiang X, Wang J. Polymorphisms of p53 and MDM2 genes are associated with severe toxicities in patients with non-small cell lung cancer. Cancer Biol Ther. 2014 Nov 2;15(11):1542-51.

48.   Zhai R, Wei Y, Su L, Liu G, Kulke M, Wain J, Christiani DC. Whole-miRNome profiling identifies prognostic serum miRNAs in esophageal adenocarcinoma: the influence of H. pylori infection status. Carcinogenesis. 2014 Nov 8. pii: bgu228. [epub ahead of print]

49.   Zhu Y, Xu H, Zhu X, Wei Y, Yang G, Xu Y, Tang L. Association between cardiothoracic ratio, left ventricular size and systolic function in patients undergoing computed tomography coronary angiography. Exp Ther Med. 2014 Dec;8(6):1757-1763. epub 2014 Oct 13.

50.   Wang Y, McKay JD, Rafnar T, Wang Z, Timofeeva MN, Broderick P, Zong X, Laplana M, Wei Y, Han Y, Lloyd A, Delahaye-Sourdeix M, Chubb D, Gaborieau V, Wheeler W, Chatterjee N, Thorleifsson G, Sulem P, Liu G, Kaaks R, Henrion M, Kinnersley B, Vallee M, LeCalvez-Kelm F, Stevens VL, Gapstur SM, Chen WV, Zaridze D, Szeszenia-Dabrowska N, Lissowska J, Rudnai P, Fabianova E, Mates D, Bencko V, Foretova L, Janout V, Krokan HE, Gabrielsen ME, Skorpen F, Vatten L, Njolstad I, Chen C, Goodman G, Benhamou S, Vooder T, Valk K, Nelis M, Metspalu A, Lener M, Lubinski J, Johansson M, Vineis P, Agudo A, Clavel-Chapelon F, Bueno-de-Mesquita HB, Trichopoulos D, Khaw KT, Johansson M, Weiderpass E, Tjonneland A, Riboli E, Lathrop M, Scelo G, Albanes D, Caporaso NE, Ye Y, Gu J, Wu X, Spitz MR, Dienemann H, Rosenberger A, Su L, Matakidou A, Eisen T, Stefansson K, Risch A, Chanock SJ, Christiani DC, Hung RJ, Brennan P, Landi MT, Houlston RS, Amos CI. Rare variants of large effect in BRCA2 and CHEK2 affect risk of lung cancer. Nature genetics. 2014;46(7):736-741.

51.   Wang T, Liu Z, Wang Z, Duan M, Li G, Wang S, Li W, Zhu Z, Wei Y, Christiani DC, Li A, Zhu X. Thrombocytopenia is associated with acute respiratory distress syndrome mortality: an international study. PLoS One. 2014; 9(4): e94124.

52.   Tejera P, O'Mahony DS, Owen CA, Wei Y, Wang Z, Gupta K, Su L, Villar J, Wurfel M, Christiani DC. Functional characterization of polymorphisms in the PI3 (elafin) gene and validation of their contribution to risk of ARDS. Am J Respir Cell Mol Biol.  2014.

53.   Gou J, Zhao Y, Wei Y, Wu C, Zhang R, Qiu Y, Zeng P, Tan W, Yu D, Wu T, Hu Z, Lin D, Shen H, Chen F. Stability SCAD: a powerful approach to detect interactions in large-scale genomic study. BMC Bioinformatics. 2014; 15: 62.

54.   Zhang R, Chu M, Zhao Y, Wu C, Guo H, Shi Y, Dai J, Wei Y, Jin G, Ma H, Dong J, Yi H, Bai J, Gong J, Sun C, Zhu M, Wu T, Hu Z, Lin D, Shen H, Chen F. A genome-wide gene-environment interaction analysis for tobacco smoke and lung cancer susceptibility. Carcinogenesis. 2014; 35(7): 1528-35.

55.   Chu M, Zhang R, Zhao Y, Wu C, Guo H, Zhou B, Lu J, Shi Y, Dai J, Jin G, Ma H, Dong J, Wei Y, Wang C, Gong J, Sun C, Zhu M, Qiu Y, Wu T, Hu Z, Lin D, Shen H, Chen F. A genome-wide gene-gene interaction analysis identifies an epistatic gene pair for lung cancer susceptibility in Han Chinese. Carcinogenesis. 2014; 35(3): 572-7.

56.   Zeng P, Wei Y, Zhao Y, Liu J, Liu L, Zhang R, Gou J, Huang S, Chen F. Variable selection approach for zero-inflated count data via adaptive lasso. Journal of Applied Statistics. 2014; 4(41): 879-894.

57.   Yongyue WeiZhaoxi WangLi Su David C. Christiani. Gene Connectivity And Variance Of  Expression In Lung Cancer. American Journal of Respiratory and Critical Care Medicine 2014;189:A4425. Conference Abstract.

58.   Cheng-Yu Chen, Ian BarnettEdnan BajwaYongyue WeiZhaoxi WangLi SuDavid C. Christiani. Genetic Regulation Of Soluble Suppression Of  Tumorigenicity-2 Expression In Acute Respiratory Distress Syndrome. American Journal of Respiratory and Critical Care Medicine 2014;189:A2781

59.   Wang J, Wei Y, Diao F, Cui Y, Mao Y, Wang W, Liu J. The association between polycystic ovary syndrome and ectopic pregnancy after in vitro fertilization and embryo transfer. Am J Obstet Gynecol. 2013, 2:139 e1-139e9.

60.   Zhai R, Yu X, Wei Y, Su L, Christiani DC.  Smoking and smoking cessation in relation to the development of co-existing non-small cell lung cancer with chronic obstructive pulmonary disease. Int J Cancer. 2013.

61.   Zhang J, Yu X, Sun B, Bai J, Wei Y, Zha X, Cui Y, Zeng M, Zhang J, Liu J, Mao H, Zhang B, Ren H, Ge Y, Xu X, Shen Z, Xing C, Cao K, Wang N. Parathyroidectomy and Heart Rate Variability in Patients with Stage 5 CKD. Clin J Am Soc Nephrol. 2013, 8: 1378-1387.

62.   Zhang R, Zhao Y, Chu M, Mehta A, Wei Y, Liu Y, Xun P, Bai J, Yu H, Su L, Zhang H, Hu Z, Shen H, Chen F, Christiani DC. A large scale gene-centric association study of lung function in newly-hired female cotton textile workers with endotoxin exposure. PLoS One, 2013, 8(3).

63.   Shouyong Gu, Xiaofei An, Liang Fang, Xiaomin Zhang, Chunyan Zhang, Jingling Wang, Qilan Liu, Yanfang Zhang, Yongyue Wei, Zhibin Hu, Feng Chen, Hongbing Shen. Risk factors and long-term health consequences of macrosomia: a prospective study in Jiangsu Province, China. Journal of biomedical research, 2012, 26(4): 235-240.

64.   Gu B, Cao Y, Pan S Zhuang L, Yu R, Peng Z, Qian H, Wei Y, Zhao L, Liu G, Tong M. Comparison of the prevalence and changing resistance to nalidixic acid and ciprofloxacin of Shigella between Europe-America and Asia-Africa from 1998 to 2009. Int J Antimicrob Agents, 2012, 40(1): 9-17.


 

中文论文:

65.   魏永越(#), 赵丽萍, 赵杨, 柏建岭, 于浩, 易洪刚, 陈峰. 生物统计专业学生实践创新能力培养模式初探. 中国卫生统计. 2016,33(6): 1079-1081.

66.   陈超,沈思鹏,赵杨,陈峰,魏永越(*). 生物统计教学中有关大数据思维与传统统计思维差异的思考. 南京医科大学学报(社会科学版). 2016, 12.

67.   魏永越(#), 荀鹏程, 余小金, 赵杨, 李瑛, 张春延, 于浩, 张肖敏, 陈峰(*). 年龄调整率的区间估计及其在宫颈癌患病率估计中的应用. 中国卫生统计. 2011.04.

68.   魏永越(#), 荀鹏程, 周敏林, 赵杨, 朱晶晶, 于浩, 陈峰(*). 自适应随机在具有响应延迟的临床试验中的应用评价. 中国临床药理学与治疗学. 2010.09.

69.   魏永越(#), 赵杨, 柏建岭, 富春枫, 于浩, 陈峰. SAS ODSRTF标记语言在临床试验规范化统计报表输出中的应用. 中国卫生统计. 2010. 08.

70.   魏永越(#*), 祝因苏, 张益红, 王丽雅, 王林. 江苏省农村人群心理健康状况调查. 中国公共卫生. 2006.02.

71.   陈梦锴, 柏建岭, 魏永越, 黄丽红, 赵杨, 于浩. 临床试验中组间不同删失率对疗效评价的影响. 中国临床药理学与治疗学. 2017, 04.

72.   武亦娴, 金琳羚, 孙理想, 魏永越, 曾晓宁, 孔辉, 谢卫平. 103NSCLC胸腔镜下肺癌根治手术后患者临床分析. 南京医科大学学报(自然科学版). 2017. 03.

73.   陆国军, 张宇, 解卫平, 曾晓宁, 孔辉, 魏永越. ESM-1CEA联合检测在鉴别良恶性胸腔积液中的价值. 南京医科大学学报(自然科学版). 2017. 01.

74.   丁海霞, 魏永越, 龚琦, 马倩, 占伊扬. 白内障摘除术费用管理中眼科日间病房的作用. 南京医科大学学报(社会科学版). 2016, 12.

75.   张秋伊, 陈峰, 魏永越, 郭丽, 赵杨. 表观基因组甲基化数据的统计分析方法. 中国卫生统计. 2016, 08.

76.   张秋伊, 赵杨, 魏永越, 张汝阳, 陈峰. 高维DNA甲基化数据的随机森林降维分析. 中华疾病控制杂志. 2016. 06.

77.   朱晓璇, 于星灿, 殷纪鹏, 赵杨, 魏永越. 非小细胞肺癌分型介导基因UCN2|90226对肺癌生存时间影响的研究. 2015(第四届)全国大学生统计建模大赛论文. 2015. 11.

78.   何帆, 高才杰, 吴伟玲, 魏永越, 郑大同. 氢化可的松治疗早产儿低血压疗效的Meta 分析. 南京医科大学学报(自然科学版). 2014. 02.

79.   刘丽亚, 陈峰, 魏永越, 娄冬华, 于浩. RPSFT法在临床试验转组研究中的应用. 中国卫生统计. 2013, 6.

80.   张艳芳, 魏永越, 陈峰, 张肖敏. 队列研究资料发病率的贝叶斯估计. 中华疾病控制杂志. 2012. 08.

81.   周定杰, 姚捷, 魏永越, 李瑛. 30T型含铜宫内节育器断裂不良事件报告分析. 国际生殖健康/计划生育杂志. 2012. 05.

82.   林洁, 魏永越, 陈峰, 于浩. 中心效应及中心间样本不均衡对临床疗效评价的影响. 中国临床药理学与治疗学. 2012. 04.

83.   雷忠英, 赵艳丰, 张益红, 魏永越. 脑梗死患者血清高半胱氨酸检测的初步应用. 临床检验杂志. 2011. 12.

84.   林玉娣, 钱云, 徐明, 钱燕华, 杨俊莹, 尤晓寅, 龚玲芬, 王瑶, 陈峰, 赵杨, 柏建岭, 魏永越, 戴俊程, 吴蕾蕾, 石平, 张毅, 曾平, 张铁梅. 无锡市城区社区自然人群糖尿病及其患病风险现况. 中华疾病控制杂志. 2011. 10.

85.   葛爱华, 魏永越, 李瑛, 吴玉麟, 彭志行, 潘丽, 张肖敏, 陈峰. 大型流行病学调查资料的数据管理和质量控制. 南京医科大学学报(自然科学版). 2011. 04.

86.   周敏林, 魏永越, 张汝阳, 朱晶晶, 于浩, 陈峰. 多阶段随机化胜者优先设计的计算机模拟试验分析. 中国临床药理学与治疗学. 2010. 08.

87.   陈建平, 魏永越, 陈峰, 于浩. 期中分析的条件把握度及样本含量再估计. 中国卫生统计. 2010. 08.

88.   陈炯华, 魏永越, 谢雁鸣. 基于SRS的中药上市后安全性信号检测方法介绍. 中成药. 2010, 06.

89.   胡道芝, 陈晓星, 魏永越. ERCP术后急性胰腺炎危险因素的Meta分析. 第十届国际治疗内镜及消化病学术会议专题报告及论文汇编. 2010. 06.

90.   朱莹, 张灿珍, 朱岩, 魏永越. 苯丁酸钠体外对YTMLC-90细胞生长的影响. 郑州大学学报(医学版). 2010. 05.

91.   戴启刚, 陈峰, 魏永越, 于浩. 临床试验中计量-反应率关系研究中的样本含量估计方法. 中国临床药理学与治疗学. 2010. 04.

92.   陈炯华, 魏永越, 孙骏, 王永炎, 谢雁鸣. 基于数据挖掘的预警方法在双黄连注射剂不良反应监测中的应用研究. 中国中药杂志. 2010. 02.

93.   陈炯华, 王永炎, 谢雁鸣, 申春悌, 俞冲, 魏永越. "病症相符/不相符"与双黄连注射液ADR/ADE的文献研究. 中成药. 2010. 01.

94.   陈炯华, 谢雁鸣, 魏永越, 俞冲, 王永炎. 从《药品不良反应信息通报》看中药不良反应现状. 中国中医急症. 2009. 10.

95.   刘晴晓, 孙静, 侯钢, 魏永越, 王筱兰, 尚晓芳, 史家波, 成为荣, 倪苏琳. 抑郁症情绪日夜变化与若干生化指标. 临床精神医学杂志. 2009. 04.

96.   余小金, 刘沛, 闵捷, 张宏, 陈炳为, 陈启光, 魏永越, 陈峰. 暴露评估中处理未检出值的多检出限回归方法及其应用. 卫生研究. 2008. 11.

97.   刘晓燕, 陈峰, 魏永越, 柏建岭, 于浩. 响应自适应随机化分组方法. 中国临床药理学与治疗学. 2008, 06.

98.   王笔金, 雷忠英, 张梅香, 王建平, 魏永越, 张益红. 西班牙LENA动态血沉分析仪的可靠性评价. 南京医科大学学报(自然科学版). 2008. 04.

99.   林晖, 魏永越. 实施"三早教育", 努力提高医学上的综合素质. 南京医科大学学报(社会科学版). 2006. 09.

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